How further suppression of virus replication could improve current HBV treatment.
作者信息
Tavis John E, Gehring Adam J, Hu Yuan
出版信息
Expert Rev Anti Infect Ther. 2013 Aug;11(8):755-7. doi: 10.1586/14787210.2013.814846.
Abstract
摘要
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How further suppression of virus replication could improve current HBV treatment.进一步抑制病毒复制如何能够改善当前的乙肝治疗。
Expert Rev Anti Infect Ther. 2013 Aug;11(8):755-7. doi: 10.1586/14787210.2013.814846.
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Antiviral Res. 2013 Apr;98(1):27-34. doi: 10.1016/j.antiviral.2013.01.006. Epub 2013 Feb 4.
2
The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes.乙型肝炎病毒核糖核酸酶 H 对人类免疫缺陷病毒核糖核酸酶 H 和整合酶酶的抑制剂敏感。
PLoS Pathog. 2013 Jan;9(1):e1003125. doi: 10.1371/journal.ppat.1003125. Epub 2013 Jan 22.
3
Hepatitis B virus reactivation associated with anti-neoplastic therapy.与抗肿瘤治疗相关的乙型肝炎病毒再激活。
J Gastroenterol Hepatol. 2013 Jan;28(1):31-7. doi: 10.1111/j.1440-1746.2012.07280.x.
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Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues.核苷（酸）类似物长期有效治疗后乙型肝炎病毒特异性 T 细胞功能的恢复。
Gastroenterology. 2012 Oct;143(4):963-73.e9. doi: 10.1053/j.gastro.2012.07.014. Epub 2012 Jul 14.
5
DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model.DNA 初免-腺病毒加强免疫可诱导小鼠和土拨鼠模型中针对嗜肝病毒蛋白的强烈和多功能 T 细胞应答。
J Virol. 2012 Sep;86(17):9297-310. doi: 10.1128/JVI.00506-12. Epub 2012 Jun 20.
6
Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation.鉴定二取代磺胺类化合物作为乙型肝炎病毒共价闭合环状 DNA 形成的特异性抑制剂。
Antimicrob Agents Chemother. 2012 Aug;56(8):4277-88. doi: 10.1128/AAC.00473-12. Epub 2012 May 29.
7
Hepatitis B therapy.乙肝治疗。
Nat Rev Gastroenterol Hepatol. 2011 May;8(5):275-84. doi: 10.1038/nrgastro.2011.33. Epub 2011 Mar 22.
8
Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines.工程病毒特异性 T 细胞，以靶向 HBV 感染的肝细胞和肝癌细胞系。
J Hepatol. 2011 Jul;55(1):103-10. doi: 10.1016/j.jhep.2010.10.025. Epub 2010 Nov 23.
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Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients.替比夫定治疗乙型肝炎 e 抗原阳性患者 3 年期间乙型肝炎表面抗原下降的动力学。
Hepatology. 2010 Nov;52(5):1611-20. doi: 10.1002/hep.23905.
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Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy.在接受抑制性抗病毒治疗的患者中，肝内和肝外乙型肝炎病毒（HBV）储库的分子特征。
J Viral Hepat. 2011 Jun;18(6):415-23. doi: 10.1111/j.1365-2893.2010.01321.x.
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