Department of Surgery, Zagreb Clinical Hospital Center, Zagreb, Croatia.
Department of Surgery and Urology, Zabok General Hospital, Zabok, Croatia.
Urology. 2014 Jan;83(1):6-11. doi: 10.1016/j.urology.2013.07.009. Epub 2013 Aug 23.
Primary melanoma of the glans or male urethra is a rare malignant tumor with high mortality. We searched PubMed and found 129 articles reporting on 220 patients. All articles were case reports or case series. Median patient age was 65 years. Median survival was 28 months, with 5-year survival in approximately 10%. All patients who survived over 5 years had a localized disease (stage I/A) with invasion depth <3-3.5 mm. Wide local excision with sentinel lymph node biopsy is the treatment of choice for patients with localized disease. For advanced disease, the prognosis is poor.
阴茎或男性尿道原发性黑色素瘤是一种罕见的恶性肿瘤，死亡率高。我们检索了 PubMed 并找到了 129 篇报道 220 例患者的文章。所有文章均为病例报告或病例系列研究。中位患者年龄为 65 岁。中位生存时间为 28 个月，5 年生存率约为 10%。所有生存时间超过 5 年的患者均为局限性疾病（Ⅰ/A 期），浸润深度<3-3.5mm。对于局限性疾病患者，首选广泛局部切除加前哨淋巴结活检。对于晚期疾病，预后较差。
