Kumar Senthil, Sahu Anurag, Jambunathan Saravanan, Chandrashekhar Shantanu, Kanakasabapathy Saravanan
Urology, SRM Medical College Hospital and Research Centre, Chennai, IND.
Cureus. 2024 Oct 18;16(10):e71819. doi: 10.7759/cureus.71819. eCollection 2024 Oct.
Penile melanoma is a rare and highly invasive cancer that is generally diagnosed in the sixth to seventh decades of life. We report a rare case of primary malignant melanoma of the glans penis in a 38-year-old man who presented with a proliferative lesion over the glans with discoloration for six months. The clinical and metastatic workups were unremarkable. Circumcision and biopsy performed outside showed characteristics of squamous cell carcinoma. We treated the patient with a partial penectomy, and the histopathological examination was suggestive of malignant melanoma. A stump revision with bilateral superficial inguinal lymph node dissection was performed. As per the oncologist's opinion, the patient underwent chemotherapy and immunotherapy after surgery. No recurrence or metastasis occurred during the one-year follow-up.
阴茎黑色素瘤是一种罕见且侵袭性很强的癌症,通常在60至70岁时被诊断出来。我们报告了一例罕见的龟头原发性恶性黑色素瘤病例,患者为一名38岁男性,龟头出现增生性病变并伴有色素沉着,持续了6个月。临床和转移灶检查均无异常。在外院进行的包皮环切术和活检显示为鳞状细胞癌特征。我们对患者进行了部分阴茎切除术,组织病理学检查提示为恶性黑色素瘤。随后进行了双侧腹股沟浅淋巴结清扫的残端修复术。根据肿瘤学家的意见,患者术后接受了化疗和免疫治疗。在一年的随访期间未出现复发或转移。