Yin Guomei, Xu Jian, Shen Zhuolan, Wang Yongjun, Zhu Faming, Lv Hangjun
Blood Center of Zhejiang Province, Hangzhou, Zhejiang, People's Republic of China.
Transfus Apher Sci. 2013 Dec;49(3):608-12. doi: 10.1016/j.transci.2013.07.028. Epub 2013 Aug 8.
Platelet yield was associated with donor's characteristic and property of apheresis instruments. Here, we have analyzed the relationship of platelet yield, physiologic parameters of donors for different apheresis instruments in China. Data were consecutively retrieved from plateletapheresis donors during March 1, 2007 and March 1, 2012. Three different apheresis instruments MCS+, Amicus, Trima system were used for plateletapheresis and defined as group 1, 2 and 3 respectively. Totally 77,091 Plateletapheresis donations were performed in this study. 17 donations were finally aborted because of vasovagal reaction with syncope. 5861, 37,036, 34,177 donations were performed in group 1, 2 and 3 respectively. Hct and platelet values before donations were similar, but platelet yield and collection rate were showed significantly difference (p<0.05) among the three groups. The values of platelet and Hct in the males before donations were higher than those in the females, and the platelet yield and collection rate were showed significantly difference between the male group and female group (p<0.05). The overall reaction rate was 1.56%. Most donors were chosen the group 2 (51.6%) for next donation, followed by group 3 (33%) and group 1 (15.4%). We concluded that the platelet yield and collection rate in the male group were higher than those in the female group and the efficiency of plateletapheresis was associated with the kind of apheresis instruments and donor's characteristic. These data will help to work out suitable apheresis protocol based on the Chinese donor's characteristic.
血小板产量与献血者特征及血液成分分离仪器的性能相关。在此，我们分析了中国不同血液成分分离仪器的血小板产量与献血者生理参数之间的关系。数据连续取自2007年3月1日至2012年3月1日期间的血小板单采献血者。使用三种不同的血液成分分离仪器MCS +、Amicus、Trima系统进行血小板单采，并分别定义为第1组、第2组和第3组。本研究共进行了77,091次血小板单采献血。最终有17次献血因血管迷走神经反应伴晕厥而中止。第1组、第2组和第3组分别进行了5861次、37,036次和34,177次献血。献血前的血细胞比容（Hct）和血小板值相似，但三组之间的血小板产量和采集率显示出显著差异（p<0.05）。男性献血前的血小板和Hct值高于女性，男性组和女性组之间的血小板产量和采集率显示出显著差异（p<0.05）。总体反应率为1.56%。大多数献血者下次献血选择第2组（51.6%），其次是第3组（33%）和第1组（15.4%）。我们得出结论，男性组的血小板产量和采集率高于女性组，血小板单采效率与血液成分分离仪器的种类和献血者特征有关。这些数据将有助于根据中国献血者的特征制定合适的血液成分分离方案。
