Miklos Rohla, 3rd Medical Department, Cardiology and Emergency Medicine, Wilhelminenhospital, Vienna, Austria, Tel. +43/1/491 50 23 01, Fax +43/1/491 50 23 09, E-mail:
Hamostaseologie. 2013;33(4):283-94. doi: 10.5482/HAMO-13-07-0035. Epub 2013 Aug 27.
Extensive research of the past decades altered our traditional concept about the genesis of atherosclerosis fundamentally. Today, the crucial role of inflammation in the formation and progression of atherosclerotic plaques is indisputable. Patients at high risk for developing cardiovascular disease, owing to poor diet, obesity and low physical activity have been shown to exhibit a particular inflammatory pattern. Therefore, the present review highlights the crosslink between the metabolic syndrome (MetS), adipose tissue, adipokines and selected inflammatory cytokines in the context of atherothrombosis and cardiovascular disease.
过去几十年的广泛研究从根本上改变了我们对动脉粥样硬化发生的传统观念。如今，炎症在动脉粥样硬化斑块的形成和发展中的关键作用是无可争议的。由于不良饮食、肥胖和低体力活动，有发生心血管疾病高风险的患者表现出一种特殊的炎症模式。因此，本综述强调了代谢综合征（MetS）、脂肪组织、脂肪因子和选定的炎症细胞因子在动脉血栓形成和心血管疾病中的相互关系。
