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荧光成像是可生物降解的光稳定聚合物胶束的实现手段。

Fluorescence imaging enabled biodegradable photostable polymeric micelles.

机构信息

Department of Bioengineering The University of Texas at Arlington Arlington, TX 76010, USA.

出版信息

Adv Healthc Mater. 2014 Feb;3(2):182-6. doi: 10.1002/adhm.201300145. Epub 2013 Aug 26.

DOI:10.1002/adhm.201300145
PMID:23983129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3844036/
Abstract

Amphiphilic biodegradable photoluminescent polymers (ABPLPs) composed of a biodegradable fluorescent polymer and methoxy poly (ethyleneglycol) demonstrate intrinsic bright, tunable, and stable fluorescence emission. ABPLP micelles elicit minor cellular toxicity and can be used for cell and tissue imaging both in vitro and in vivo.

摘要

两亲性可生物降解光致发光聚合物（ABPLP）由可生物降解荧光聚合物和甲氧基聚（乙二醇）组成，具有内在的明亮、可调谐且稳定的荧光发射。ABPLP 胶束引起的细胞毒性较小，可用于体外和体内的细胞和组织成像。

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