Rahmatullah Mohammed, Azam Md Nur Kabidul, Khatun Zubaida, Seraj Syeda, Islam Farhana, Rahman Md Atiqur, Jahan Sharmin, Aziz Md Shah
Faculty of Life Sciences, University of Development Alternative, Dhanmondi, Dhaka-1205, Bangladesh.
Afr J Tradit Complement Altern Med. 2012 Apr 2;9(3):380-5. doi: 10.4314/ajtcam.v9i3.12. eCollection 2012.
Diabetes mellitus is an endocrinological disorder arising from insulin deficiency or due to ineffectiveness of the insulin produced by the body. This results in high blood glucose and with time, to neurological, cardiovascular, retinal and renal complications. It is a debilitating disease and affects the population of every country of the world. Around 200 million people of the world suffer from this disease and this figure is projected to rise to 300 million in the coming years. The disease cannot be cured with allopathic medicine as the drugs used do not restore normal glucose homeostasis and moreover have side-effects. On the other hand, traditional medicinal practitioners of various countries claim to cure diabetes or at least alleviate the major symptoms and progression of this disease through administration of medicinal plants. The Garos are an indigenous community of Bangladesh, who still follow their traditional medicinal practices. Their traditional medicinal formulations contain a number of plants, which they claim to be active antidiabetic agents. Since observation of indigenous practices have led to discovery of many modern drugs, it was the objective of the present study to conduct a survey among the Marakh sect of the Garos residing in Mymensingh district of Bangladesh to find out the medicinal plants that they use for treatment of diabetes. It was found that the tribal practitioners of the Marakh sect of the Garos use twelve medicinal plants for treatment of diabetes. These plants were Lannea coromandelica, Alstonia scholaris, Catharanthus roseus, Enhydra fluctuans, Terminalia chebula, Coccinia grandis, Momordica charantia, Cuscuta reflexa, Phyllanthus emblica, Syzygium aqueum, Drynaria quercifolia, and Clerodendrum viscosum. A review of the scientific literature demonstrated that almost all the plants used by the Garo tribal practitioners have reported antidiabetic and/or antioxidant properties and have enormous potential for possible development of new and efficacious antidiabetic drugs.
糖尿病是一种内分泌紊乱疾病,起因是胰岛素缺乏或机体产生的胰岛素无效。这会导致血糖升高,随着时间推移,还会引发神经、心血管、视网膜和肾脏并发症。它是一种使人衰弱的疾病,影响着世界各国的人口。全球约有2亿人患有这种疾病,预计这一数字在未来几年将升至3亿。西医无法治愈这种疾病,因为所用药物无法恢复正常的葡萄糖稳态,而且还有副作用。另一方面,各国的传统医学从业者声称可以通过使用药用植物治愈糖尿病,或至少缓解该疾病的主要症状及病情发展。加罗人是孟加拉国的一个本土社区,他们仍遵循传统医学做法。他们的传统药物配方包含多种植物,他们称这些植物是有效的抗糖尿病药物。由于对本土做法的观察已促成许多现代药物的发现,本研究的目的是对居住在孟加拉国迈门辛希区的加罗马拉克教派进行调查,以找出他们用于治疗糖尿病的药用植物。结果发现,加罗马拉克教派的部落行医者使用12种药用植物治疗糖尿病。这些植物分别是:柯氏榄仁、印度鸡骨常山、长春花、水蕹、诃子、大籽南瓜、苦瓜、菟丝子、余甘子、水蒲桃、槲叶骨碎补和黏毛大青。对科学文献的综述表明,加罗部落行医者使用的几乎所有植物都有抗糖尿病和/或抗氧化特性,在开发新的有效抗糖尿病药物方面具有巨大潜力。