Department of Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Evid Based Complement Alternat Med. 2013;2013:162501. doi: 10.1155/2013/162501. Epub 2013 Aug 1.
Aims. To investigate the treatment of hospitalized patients with coronary artery disease (CAD) and the prognostic factors in Beijing, China. Materials and Methods. A multicenter prospective study was conducted through an integrative platform of clinical and research at 12 hospitals in Beijing, China. The clinical information of 3537 hospitalized patients with CAD was collected from September 2009 to May 2011, and the efficacy of secondary prevention during one-year followup was evaluated. In addition, a logistic regression analysis was performed to identify some factors which will have independent impact on the prognosis. Results. The average age of all patients was 64.88 ± 11.97. Of them, 65.42% are males. The medicines for patients were as follows: antiplatelet drugs accounting for 91.97%, statins accounting for 83.66%, β -receptor blockers accounting for 72.55%, ACEI/ARB accounting for 58.92%, and revascularization (including PCI and CABG) accounting for 40.29%. The overall incidence of cardiovascular events was 13.26% (469/3537). The logistic stepwise regression analysis showed that heart failure (OR, 3.707, 95% CI = 2.756-4.986), age ≥ 65 years old (OR, 2.007, 95% CI = 1.587-2.53), and myocardial infarction (OR, 1.649, 95% CI = 1.322-2.057) were the independent risk factors of others factors for cardiovascular events that occurred during followup of one-year period. Integrative medicine (IM) therapy showed the beneficial tendency for decreasing incidence of cardiovascular events, although no statistical significance was found (OR, 0.797, 95% CI = 0.613~1.036). Conclusions. Heart failure, age ≥ 65 years old, and myocardial infarction were associated with an increase in incidence of cardiovascular events, and treatment with IM showed a tendency for decreasing incidence of cardiovascular events.
目的。研究中国北京住院冠心病（CAD）患者的治疗方法和预后因素。材料和方法。通过中国北京 12 家医院的临床和研究综合平台，进行了一项多中心前瞻性研究。2009 年 9 月至 2011 年 5 月期间，收集了 3537 例住院 CAD 患者的临床信息，并评估了一年随访期间的二级预防效果。此外，还进行了逻辑回归分析，以确定对预后有独立影响的一些因素。结果。所有患者的平均年龄为 64.88 ± 11.97 岁。其中，65.42%为男性。患者使用的药物如下：抗血小板药物占 91.97%，他汀类药物占 83.66%，β受体阻滞剂占 72.55%，ACEI/ARB 占 58.92%，血管重建术（包括 PCI 和 CABG）占 40.29%。心血管事件的总发生率为 13.26%（469/3537）。逻辑逐步回归分析表明，心力衰竭（OR，3.707，95%CI=2.756-4.986）、年龄≥65 岁（OR，2.007，95%CI=1.587-2.53）和心肌梗死（OR，1.649，95%CI=1.322-2.057）是随访 1 年内发生其他心血管事件的独立危险因素。尽管没有统计学意义（OR，0.797，95%CI=0.613-1.036），但综合医学（IM）治疗显示出降低心血管事件发生率的趋势。结论。心力衰竭、年龄≥65 岁和心肌梗死与心血管事件发生率的增加相关，IM 治疗显示出降低心血管事件发生率的趋势。
