Chhakchhuak Christine L, Khosravi Mehdi, Lohr Kristine M
Division of Rheumatology, Department of Internal Medicine, University of Kentucky, 740 South Limestone Street, Room J-515, Lexington, KY 40536, USA.
Case Rep Rheumatol. 2013;2013:621340. doi: 10.1155/2013/621340. Epub 2013 Jul 25.
Flourine-18 fluoro-2-deoxy-glucose ((18)F-FDG) positron emission tomography combined with computed tomography (PET/CT) is a useful test for the management of malignant conditions. Inflammatory and infectious processes, however, can cause increased uptake on PET scanning, often causing diagnostic dilemmas. This knowledge is important to the rheumatologist not only because of the inflammatory conditions we treat but also because certain rheumatic diseases impose an increased risk of malignancy either due to the disease itself or as a consequence of medications used to treat the rheumatic diseases. There is an increasing body of evidence investigating the role of PET scans in inflammatory conditions. This paper describes a patient with rheumatoid arthritis who developed pulmonary nodules that showed increased uptake on PET/CT scan and reviews the use of PET scanning in the diagnosis and management of rheumatoid arthritis.
氟-18氟代脱氧葡萄糖（(18)F-FDG）正电子发射断层扫描联合计算机断层扫描（PET/CT）是用于恶性疾病管理的一项有用检查。然而，炎症和感染过程可导致PET扫描时摄取增加，常引发诊断难题。这一知识对风湿病学家很重要，不仅因为我们治疗的炎症性疾病，还因为某些风湿性疾病由于疾病本身或用于治疗风湿性疾病的药物而使患恶性肿瘤的风险增加。有越来越多的证据在研究PET扫描在炎症性疾病中的作用。本文描述了一名类风湿关节炎患者，其肺部结节在PET/CT扫描中显示摄取增加，并综述了PET扫描在类风湿关节炎诊断和管理中的应用。
