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精神分裂症认知功能对多维结局测量的直接和间接影响:功能能力的作用。

Direct and mediated effects of cognitive function with multidimensional outcome measures in schizophrenia: the role of functional capacity.

机构信息

a Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California , San Diego , CA , USA.

出版信息

J Clin Exp Neuropsychol. 2013;35(8):882-95. doi: 10.1080/13803395.2013.828021. Epub 2013 Aug 28.

DOI:10.1080/13803395.2013.828021
PMID:23984631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3789849/
Abstract

Although cognitive ability is a known predictor of real-world functioning in schizophrenia, there has been an expanded interest in understanding the mechanisms by which it explains real-world functioning in this population. We examined the extent to which functional capacity (i.e., skills necessary to live independently) mediated the relationship between cognitive ability and both observer and self-reported real-world functioning in 138 outpatients with schizophrenia. Functional capacity significantly mediated the relations between cognitive ability and observer-rated real-world functioning, but not self-reported real-world functioning, with small to medium effect sizes observed for all outcomes. The role of cognitive ability in observer versus self-reported real-world functioning may be explained by different mechanisms.

摘要

虽然认知能力是精神分裂症患者在现实生活中表现的已知预测因素,但人们越来越关注理解认知能力在该人群中解释现实生活表现的机制。我们研究了在 138 名精神分裂症门诊患者中,功能能力(即独立生活所需的技能)在多大程度上调节了认知能力与观察者和自我报告的现实生活功能之间的关系。功能能力显著调节了认知能力与观察者评定的现实生活功能之间的关系,但与自我报告的现实生活功能无关,所有结果的效应大小均为小到中等。认知能力在观察者评定的现实生活功能与自我报告的现实生活功能之间的作用可能由不同的机制来解释。

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本文引用的文献

1
Predictors of the accuracy of self assessment of everyday functioning in people with schizophrenia.预测精神分裂症患者日常功能自我评估准确性的因素。
Schizophr Res. 2012 May;137(1-3):190-5. doi: 10.1016/j.schres.2012.02.002. Epub 2012 Mar 2.
2
When functional capacity and real-world functioning converge: the role of self-efficacy.当功能能力和现实世界的功能趋于一致时:自我效能的作用。
Schizophr Bull. 2013 Jul;39(4):908-16. doi: 10.1093/schbul/sbs004. Epub 2012 Feb 10.
3
The influence of demographic factors on functional capacity and everyday functional outcomes in schizophrenia.人口统计学因素对精神分裂症患者的功能能力和日常功能结局的影响。
J Clin Exp Neuropsychol. 2012;34(5):467-75. doi: 10.1080/13803395.2011.651102. Epub 2012 Jan 25.
4
Effect size measures for mediation models: quantitative strategies for communicating indirect effects.中介模型的效应量度量:沟通间接效应的定量策略。
Psychol Methods. 2011 Jun;16(2):93-115. doi: 10.1037/a0022658.
5
Neurocognitive predictors of objective and subjective quality of life in individuals with schizophrenia: a meta-analytic investigation.精神分裂症个体的神经认知预测因子与客观和主观生活质量:一项荟萃分析研究。
Schizophr Bull. 2012 Mar;38(2):304-15. doi: 10.1093/schbul/sbq077. Epub 2010 Jul 11.
6
The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis.精神分裂症患者的神经认知与社会认知功能与功能结局的关系:一项荟萃分析。
Neurosci Biobehav Rev. 2011 Jan;35(3):573-88. doi: 10.1016/j.neubiorev.2010.07.001. Epub 2010 Jul 8.
7
What do we know about neuropsychological aspects of schizophrenia?我们对精神分裂症的神经心理学方面了解多少?
Neuropsychol Rev. 2009 Sep;19(3):365-84. doi: 10.1007/s11065-009-9109-y. Epub 2009 Jul 30.
8
Symptoms as mediators of the relationship between neurocognition and functional outcome in schizophrenia: a meta-analysis.症状作为精神分裂症神经认知与功能结局关系的中介因素:一项荟萃分析。
Schizophr Res. 2009 Sep;113(2-3):189-99. doi: 10.1016/j.schres.2009.03.035. Epub 2009 Jul 22.
9
Schizophrenia, "just the facts": what we know in 2008 Part 3: neurobiology.精神分裂症,“只讲事实”:2008年我们所了解的情况 第三部分:神经生物学
Schizophr Res. 2008 Dec;106(2-3):89-107. doi: 10.1016/j.schres.2008.07.020. Epub 2008 Sep 16.
10
Abbreviated neuropsychological assessment in schizophrenia: prediction of different aspects of outcome.精神分裂症的简短神经心理学评估:结局不同方面的预测
J Clin Exp Neuropsychol. 2009 May;31(4):462-71. doi: 10.1080/13803390802251386.