Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an, 710069, P. R. China.
Org Lett. 2013 Sep 20;15(18):4822-5. doi: 10.1021/ol4022222. Epub 2013 Aug 29.
A novel Cu(TFA)2-catalyzed oxidative tandem cyclization/1,2-alkyl migration of readily available enamino amides for the synthesis of pyrrolin-4-ones has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the rapid synthesis of substituted pyrrolin-4-ones in high yields under mild conditions.
一种新型的 Cu(TFA)2 催化的氧化串联环化/1,2-烷基迁移反应，用于 readily available enamino amides 的合成 pyrrolin-4-ones 已被开发出来。该反应可以容忍广泛的官能团，是一种在温和条件下快速合成取代 pyrrolin-4-ones 的可靠方法，产率高。
