Department of Psychology, University of California, Berkeley, USA.
Clin Psychol Rev. 2013 Dec;33(8):914-28. doi: 10.1016/j.cpr.2013.07.001. Epub 2013 Jul 16.
Schizophrenia can be a chronic and debilitating psychiatric disorder. Though advancements have been made in the psychosocial treatment of some symptoms of schizophrenia, people with schizophrenia often continue to experience some level of symptoms, particularly negative symptoms, throughout their lives. Because negative symptoms are associated with poor functioning and quality of life, the treatment of negative symptoms is a high priority for intervention development. However, current psychosocial treatments primarily focus on the reduction of positive symptoms with comparatively few studies investigating the efficacy of psychosocial treatments for negative symptoms. In this article, we review and evaluate the existing literature on three categories of psychosocial treatments--cognitive behavioral therapy (CBT), social skills training (SST), and combined treatment interventions--and their impact on the negative symptoms of schizophrenia. Of the interventions reviewed, CBT and SST appear to have the most empirical support, with some evidence suggesting that CBT is associated with maintenance of negative symptom improvement beyond six months after treatment. It remains unclear if a combined treatment approach provides improvements above and beyond those associated with each individual treatment modality. Although psychosocial treatments show promise for the treatment of negative symptoms, there are many unanswered questions about how best to intervene. We conclude with a general discussion of these unanswered questions, future directions and methodological considerations, and suggestions for the further development of negative symptom interventions.
精神分裂症是一种慢性且使人虚弱的精神疾病。尽管在精神社交治疗某些精神分裂症症状方面已经取得了进展,但精神分裂症患者在其一生中往往仍会经历某种程度的症状,尤其是阴性症状。由于阴性症状与功能不良和生活质量差有关,因此干预措施的开发应将阴性症状的治疗作为重中之重。然而,目前的精神社交治疗主要侧重于减轻阳性症状,而很少有研究调查精神社交治疗对阴性症状的疗效。在本文中,我们回顾和评估了认知行为疗法(CBT)、社交技能训练(SST)和联合治疗干预这三类精神社交治疗方法及其对精神分裂症阴性症状的影响。在回顾的干预措施中,CBT 和 SST 似乎具有最多的实证支持,有证据表明 CBT 与治疗后六个月后阴性症状改善的维持有关。目前尚不清楚联合治疗方法是否能提供比单独使用每种治疗模式更好的改善效果。尽管精神社交治疗在治疗阴性症状方面显示出一定的前景,但对于如何进行干预仍存在许多悬而未决的问题。我们在文章结尾部分对这些未解决的问题、未来的研究方向和方法学考虑因素以及对阴性症状干预措施的进一步发展进行了讨论。