Civil and Environmental Engineering Department, 418 Durham Hall, Virginia Tech, Blacksburg, VA 24061, USA.
Sci Total Environ. 2014 Jan 1;466-467:1011-21. doi: 10.1016/j.scitotenv.2013.07.111. Epub 2013 Aug 28.
The risk of students to develop elevated blood lead from drinking water consumption at schools was assessed, which is a different approach from predictions of geometric mean blood lead levels. Measured water lead levels (WLLs) from 63 elementary schools in Seattle and 601 elementary schools in Los Angeles were acquired before and after voluntary remediation of water lead contamination problems. Combined exposures to measured school WLLs (first-draw and flushed, 50% of water consumption) and home WLLs (50% of water consumption) were used as inputs to the Integrated Exposure Uptake Biokinetic (IEUBK) model for each school. In Seattle an average 11.2% of students were predicted to exceed a blood lead threshold of 5 μg/dL across 63 schools pre-remediation, but predicted risks at individual schools varied (7% risk of exceedance at a "low exposure school", 11% risk at a "typical exposure school", and 31% risk at a "high exposure school"). Addition of water filters and removal of lead plumbing lowered school WLL inputs to the model, and reduced the predicted risk output to 4.8% on average for Seattle elementary students across all 63 schools. The remnant post-remediation risk was attributable to other assumed background lead sources in the model (air, soil, dust, diet and home WLLs), with school WLLs practically eliminated as a health threat. Los Angeles schools instead instituted a flushing program which was assumed to eliminate first-draw WLLs as inputs to the model. With assumed benefits of remedial flushing, the predicted average risk of students to exceed a BLL threshold of 5 μg/dL dropped from 8.6% to 6.0% across 601 schools. In an era with increasingly stringent public health goals (e.g., reduction of blood lead safety threshold from 10 to 5 μg/dL), quantifiable health benefits to students were predicted after water lead remediation at two large US school systems.
评估了学生因在学校饮用含铅水而导致血铅升高的风险,这与预测几何平均血铅水平的方法不同。在西雅图的 63 所小学和洛杉矶的 601 所小学中,在自愿纠正了涉铅水污染问题之前和之后,均采集了测量的饮用水铅含量水平(WLL)。将测量的学校 WLL(首次抽取和冲洗,占饮用水消耗量的 50%)和家庭 WLL(占饮用水消耗量的 50%)的综合暴露量用作每个学校的综合暴露摄入生物动力学模型(IEUBK)的输入。在西雅图,在进行补救措施之前,有 63 所学校中有 11.2%的学生预计会超过 5μg/dL 的血铅阈值,但各个学校的预测风险存在差异(“低暴露学校”的风险为 7%,“典型暴露学校”的风险为 11%,“高暴露学校”的风险为 31%)。添加水过滤器并更换含铅管道可降低模型中的学校 WLL 输入,从而使西雅图所有 63 所小学的学生的平均预测风险降低至 4.8%。补救措施之后残留的风险归因于模型中其他假设的背景铅源(空气、土壤、灰尘、饮食和家庭 WLL),而学校 WLL 实际上已不再构成健康威胁。洛杉矶的学校则实施了冲洗计划,该计划被认为可以消除模型中的首次抽取 WLL 作为输入。假设补救性冲洗的好处,在 601 所学校中,学生超过 5μg/dL 的血铅浓度阈值的平均预测风险从 8.6%下降到 6.0%。在一个公共卫生目标日益严格的时代(例如,将血铅安全阈值从 10μg/dL 降低到 5μg/dL),对美国两个大型学校系统进行了饮用水铅治理之后,预计会对学生产生可量化的健康益处。