Cook Elizabeth A, Liu Nancy H, Tarasenko Melissa, Davidson Charlie A, Spaulding William D
Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE 68588-0308, USA.
J Nerv Ment Dis. 2013 Sep;201(9):786-94. doi: 10.1097/NMD.0b013e3182a2140b.
The purpose of this study was to examine relationships between neurocognition, theory of mind, and community functioning in a sample of 43 outpatients with serious mental illness (SMI). Relationships between baseline values and changes over time were analyzed using multilevel modeling. The results showed that a) neurocognition and theory of mind were each associated with community functioning at baseline, b) community functioning improved during approximately 12 months of treatment, c) greater improvement in neurocognition over time predicted higher rates of improvement in community functioning, d) theory of mind did not predict change in community functioning after controlling for neurocognition, and e) the effect of change in neurocognition on community functioning did not depend on the effect of baseline neurocognition. This study provides empirical support that individuals with SMI may experience improvement in community functioning, especially when they also experience improvement in neurocognition. Limitations and recommendations for future research are discussed.
本研究旨在调查43名患有严重精神疾病(SMI)的门诊患者样本中神经认知、心理理论与社区功能之间的关系。使用多层次模型分析了基线值与随时间变化之间的关系。结果表明:a)神经认知和心理理论在基线时均与社区功能相关;b)在大约12个月的治疗期间,社区功能有所改善;c)随着时间推移,神经认知的更大改善预示着社区功能的更高改善率;d)在控制神经认知后,心理理论并不能预测社区功能的变化;e)神经认知变化对社区功能的影响并不取决于基线神经认知的影响。本研究提供了实证支持,即患有严重精神疾病的个体可能在社区功能方面有所改善,尤其是当他们在神经认知方面也有所改善时。文中讨论了研究的局限性以及对未来研究的建议。