精神分裂症的神经认知、心理理论、社会能力、阴性症状与现实世界功能的路径模型研究。
A path model investigation of neurocognition, theory of mind, social competence, negative symptoms and real-world functioning in schizophrenia.
机构信息
University of Maryland College Park, 1123M Biology-Psychology Building, College Park, MD 20742, USA.
出版信息
Schizophr Res. 2011 Feb;125(2-3):152-60. doi: 10.1016/j.schres.2010.09.020. Epub 2010 Oct 20.
Abstract
Problems in real-world functioning are pervasive in schizophrenia and much recent effort has been devoted to uncovering factors which contribute to poor functioning. The goal of this study was to examine the role of four such factors: social cognition (theory of mind), neurocognition, negative symptoms, and functional capacity (social competence). 178 individuals with schizophrenia or schizoaffective disorder completed measures of theory of mind, neurocognition, negative symptoms, social competence, and self-reported functioning. Path models sought to determine the relationships among these variables. Theory of mind as indexed by the Hinting Task partially mediated the relationship between neurocognition and social competence, and negative symptoms and social competence demonstrated significant direct paths with self-reported functioning. Study results suggest theory of mind serves as an important mediator in addition to previously investigated social cognitive domains of emotional and social perception. The current study also highlights the need to determine variables which mediate the relationship between functional capacity and real-world functioning.
摘要
现实世界功能障碍在精神分裂症中普遍存在，最近人们做出了很大努力来揭示导致功能障碍的因素。本研究的目的是检验以下四个因素的作用：社会认知（心理理论）、神经认知、阴性症状和功能能力（社交能力）。178 名精神分裂症或分裂情感障碍患者完成了心理理论、神经认知、阴性症状、社交能力和自我报告功能的测量。路径模型旨在确定这些变量之间的关系。由暗示任务索引的心理理论部分中介了神经认知和社交能力之间的关系，阴性症状和社交能力与自我报告的功能之间存在显著的直接关系。研究结果表明，心理理论除了先前研究过的情绪和社会感知等社会认知领域外，还是一个重要的中介因素。本研究还强调需要确定功能能力和现实世界功能之间关系的中介变量。
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