Universidad Europea Madrid, Madrid, Spain.
Physiology (Bethesda). 2013 Sep;28(5):330-58. doi: 10.1152/physiol.00019.2013.
The concept of a "polypill" is receiving growing attention to prevent cardiovascular disease. Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free intervention for which our genome has been haped over evolution. Compared with drugs, exercise is available at low cost and relatively free of adverse effects. We summarize epidemiological evidence on the preventive/therapeutic benefits of exercise and on the main biological mediators involved.
“复方药丸”这一概念越来越受到关注，以预防心血管疾病。然而，经常锻炼也可以带来类似甚至更高的益处，而且这是一种无需药物的干预措施，我们的基因组在进化过程中已经适应了这种干预措施。与药物相比，锻炼的成本低，且副作用相对较少。我们总结了关于锻炼的预防/治疗益处以及涉及的主要生物学介质的流行病学证据。
