Department of Microbiology, University of Dhaka, Dhaka, 1000 Bangladesh.
Indian J Microbiol. 2012 Sep;52(3):400-5. doi: 10.1007/s12088-012-0247-1. Epub 2012 Mar 31.
The present study investigates into some socio-economic, demographic, and nutritional features that can predispose Bangladeshi children to malnutrition and Shigella flexneri infection. Significant prognostic indicators associated with malnutrition were mother's illiteracy (unadjusted odds ratio, OR = 2.580; 95% confidence interval, CI = 1.134-5.867 and adjusted odds ratio, ORa, 3.814; 95% CI = 1.124-12.943), low birth weight (OR = 3.143; 95% CI = 1.2-8.232 and ORa = 2.404; 95% CI = 0.870-6.644) and poor socioeconomic status (OR = 2.549; 95% CI = 1.382-4.701 and ORa = 1.808; 95% CI = 0.852-3.838). Age was the strongest predictor for the acquisition of S. flexneri infection in the studied population (OR = 5.472; 95% CI = 2.583-11.592 and ORa = 5.808; 95% CI = 2.420-13.942). The severity of malnutrition was significantly (P = 0.033) related to seroprevalence of S. flexneri infection. To reduce malnutrition emphasis should be given on controlling the incidence of low birth weight, improving the literacy status especially of mothers and narrowing the gap between different socio-economic levels. Malnourished children should be examined for severity and direct intervention therapy should be given when necessary.
本研究调查了一些社会经济、人口统计学和营养特征,这些特征可能使孟加拉国儿童易患营养不良和福氏志贺菌感染。与营养不良相关的显著预后指标包括母亲文盲(未调整优势比,OR=2.580;95%置信区间,CI=1.134-5.867 和调整优势比,ORa=3.814;95%CI=1.124-12.943)、低出生体重(OR=3.143;95%CI=1.2-8.232 和 ORa=2.404;95%CI=0.870-6.644)和贫困社会经济地位(OR=2.549;95%CI=1.382-4.701 和 ORa=1.808;95%CI=0.852-3.838)。年龄是研究人群中获得福氏志贺菌感染的最强预测因素(OR=5.472;95%CI=2.583-11.592 和 ORa=5.808;95%CI=2.420-13.942)。营养不良的严重程度与福氏志贺菌感染的血清流行率显著相关(P=0.033)。为了减少营养不良,应重点控制低出生体重的发生率,提高母亲的文化程度,缩小不同社会经济水平之间的差距。应检查营养不良儿童的严重程度,并在必要时给予直接干预治疗。