北虫草的化学成分。
Chemical Ingredients of Cordyceps militaris.
作者信息
Hur Hyun
机构信息
Department of Life Science, Dongguk University, Seoul 100-715, Korea.
出版信息
Mycobiology. 2008 Dec;36(4):233-5. doi: 10.4489/MYCO.2008.36.4.233. Epub 2008 Dec 31.
Abstract
Medicinal mushrooms, including Cordyceps militaris, have received attention in Korea because of their biological activities. In the fruiting body and in corpus of C. militaris, the total free amino acid content was 69.32 mg/g and 14.03 mg/g, respectively. In the fruiting body, the most abundant amino acids were lysine, glutamic acid, proline and threonine. The fruiting body was rich in unsaturated fatty acids, which comprised about 70% of the total fatty acids. The most abundant unsaturated acid was linoleic acid. There were differences in adenosine and cordycepin contents between the fruiting body and the corpus. The adenosine concentration was 0.18% in the fruiting body and 0.06% in the corpus, and the cordycepin concentration was 0.97% in the fruiting body and 0.36% in the corpus.
摘要
包括北虫草在内的药用真菌因其生物活性在韩国受到关注。在北虫草的子实体和虫体中，总游离氨基酸含量分别为69.32毫克/克和14.03毫克/克。在子实体中，含量最丰富的氨基酸是赖氨酸、谷氨酸、脯氨酸和苏氨酸。子实体富含不饱和脂肪酸，约占总脂肪酸的70%。最丰富的不饱和酸是亚油酸。子实体和虫体中的腺苷和虫草素含量存在差异。腺苷浓度在子实体中为0.18%，在虫体中为0.06%；虫草素浓度在子实体中为0.97%，在虫体中为0.36%。
相似文献
1
Chemical Ingredients of Cordyceps militaris.北虫草的化学成分。
Mycobiology. 2008 Dec;36(4):233-5. doi: 10.4489/MYCO.2008.36.4.233. Epub 2008 Dec 31.
2
Chemical Composition and Medicinal Value of Fruiting Bodies and Submerged Cultured Mycelia of Caterpillar Medicinal Fungus Cordyceps militaris CBS-132098 (Ascomycetes).蛹虫草CBS - 132098（子囊菌）子实体和深层培养菌丝体的化学成分及药用价值
Int J Med Mushrooms. 2015;17(7):649-59. doi: 10.1615/intjmedmushrooms.v17.i7.50.
3
Optimization of solid state culture conditions for the production of adenosine, cordycepin, and D-mannitol in fruiting bodies of medicinal caterpillar fungus Cordyceps militaris (L.:Fr.) Link (Ascomycetes).蛹虫草（子囊菌纲）子实体中腺苷、虫草素和D-甘露醇生产的固态培养条件优化
Int J Med Mushrooms. 2012;14(2):181-7. doi: 10.1615/intjmedmushr.v14.i2.60.
4
The molecular recognition of cordycepin arabinoside and analysis of changes on cordycepin and its arabinoside in fruiting body and pupa of Cordyceps militaris.虫草素阿拉伯糖苷的分子识别及蛹虫草子实体和蛹中虫草素及其阿拉伯糖苷变化分析。
Food Chem. 2022 Sep 30;389:133070. doi: 10.1016/j.foodchem.2022.133070. Epub 2022 Apr 25.
5
Ethanolic extract from fruiting bodies of Cordyceps militaris HL8 exhibits cytotoxic activities against cancer cells, skin pathogenic yeasts, and postharvest pathogen Penicillium digitatum.蜜环菌子实体的醇提物 HL8 对癌细胞、皮肤病原性酵母菌和采后病原菌柑橘青霉具有细胞毒性活性。
Arch Microbiol. 2024 Feb 13;206(3):97. doi: 10.1007/s00203-024-03833-8.
6
Effects of Substrates on the Production of Fruiting Bodies and the Bioactive Components by Different Cordyceps militaris Strains (Ascomycetes).不同蛹虫草菌株（子囊菌）在不同基质上产子实体和生物活性成分的影响。
Int J Med Mushrooms. 2020;22(1):55-63. doi: 10.1615/IntJMedMushrooms.2019033257.
7
Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine.蛹虫草的硒生物强化及其对亚硒酸盐、硒代硫酸盐和硒代蛋氨酸的抗氧化活性。
Biol Trace Elem Res. 2019 Feb;187(2):553-561. doi: 10.1007/s12011-018-1386-y. Epub 2018 May 31.
8
Chemical composition and nutritional and medicinal value of fruit bodies and submerged cultured mycelia of culinary-medicinal higher Basidiomycetes mushrooms.食药用高等担子菌子实体及深层培养菌丝体的化学成分、营养与药用价值
Int J Med Mushrooms. 2014;16(3):273-91. doi: 10.1615/intjmedmushr.v16.i3.80.
9
Comparison of Major Bioactive Compounds of the Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Fruiting Bodies Cultured on Wheat Substrate and Pupae.小麦基质培养的蛹虫草（子囊菌）子实体与蛹中主要生物活性成分的比较。
Int J Med Mushrooms. 2016;18(4):327-36. doi: 10.1615/IntJMedMushrooms.v18.i4.60.
10
[Assays on nutrient and effective ingredients in different parts of Cordyceps militaris].[北虫草不同部位营养成分及有效成分的测定]
Zhongguo Zhong Yao Za Zhi. 2005 May;30(9):659-61.
引用本文的文献
1
Verification of In Vitro Anticancer Activity and Bioactive Compounds in Cordyceps Militaris-Infused Sweet Potato Shochu Spirits.蛹虫草参薯烧酒的体外抗癌活性及生物活性成分验证。
Molecules. 2024 May 3;29(9):2119. doi: 10.3390/molecules29092119.
2
Ethanolic extract from fruiting bodies of Cordyceps militaris HL8 exhibits cytotoxic activities against cancer cells, skin pathogenic yeasts, and postharvest pathogen Penicillium digitatum.蜜环菌子实体的醇提物 HL8 对癌细胞、皮肤病原性酵母菌和采后病原菌柑橘青霉具有细胞毒性活性。
Arch Microbiol. 2024 Feb 13;206(3):97. doi: 10.1007/s00203-024-03833-8.
3
Effects of dietary culture supplementation on the quality, conventional characteristics, and flavor substances of Hortobágy goose meat.日粮中添加培养物对霍托巴吉鹅肉品质、常规特性及风味物质的影响。
J Anim Sci Technol. 2022 Sep;64(5):950-969. doi: 10.5187/jast.2022.e59. Epub 2022 Sep 30.
4
Inhibited Angiotensin-Converting Enzyme through Molecular Interaction between Cordycepin and ACE C-Domain.通过虫草素与血管紧张素转换酶C结构域之间的分子相互作用抑制血管紧张素转换酶
Life (Basel). 2022 Sep 19;12(9):1450. doi: 10.3390/life12091450.
5
Antileukaemic Cell Proliferation and Cytotoxic Activity of Edible Golden Cordyceps () Extracts.食用金虫草提取物的抗白血病细胞增殖及细胞毒性活性
Evid Based Complement Alternat Med. 2022 Apr 22;2022:5347718. doi: 10.1155/2022/5347718. eCollection 2022.
6
Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells.虫草素增强自然杀伤细胞 92（NK-92）细胞杀伤胆管癌细胞的作用。
Molecules. 2021 Oct 1;26(19):5973. doi: 10.3390/molecules26195973.
7
The Potential Anticancer Activity of Phytoconstituents against Gastric Cancer-A Review on In Vitro, In Vivo, and Clinical Studies.植物成分抑制胃癌的潜在抗癌活性——体外、体内和临床研究综述。
Int J Mol Sci. 2020 Nov 5;21(21):8307. doi: 10.3390/ijms21218307.
8
Efficacy of Ethyl Acetate Fraction of for Cancer-Related Fatigue in Blood Biochemical and H-Nuclear Magnetic Resonance Metabolomic Analyses.乙酸乙酯部位对癌症相关疲劳的疗效：基于血液生化和 H 核磁共振代谢组学分析。
Integr Cancer Ther. 2020 Jan-Dec;19:1534735420932635. doi: 10.1177/1534735420932635.
9
Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus and Its Nutraceutical and Therapeutic Potential.蛹虫草素的健康与福祉：一种昆虫病原药用真菌的强效生物活性代谢产物及其营养保健品和治疗潜力。
Molecules. 2020 Jun 12;25(12):2735. doi: 10.3390/molecules25122735.
10
Fermented Extract Prevents Hepatosteatosis and Adipocyte Hypertrophy in High Fat Diet-Fed Mice.发酵提取物可预防高脂饮食喂养小鼠的肝脂肪变性和脂肪细胞肥大。
Nutrients. 2019 May 6;11(5):1015. doi: 10.3390/nu11051015.
本文引用的文献
1
Chemical Components of Paecilomyces tenuipes (Peck) Samson.细脚拟青霉（Peck）Samson的化学成分。
Mycobiology. 2007 Dec;35(4):215-8. doi: 10.4489/MYCO.2007.35.4.215. Epub 2007 Dec 31.
2
Methanol extract of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-kappaB activation.粉被虫草甲醇提取物通过抑制核因子κB激活来抑制体内外炎症介质。
Toxicol Appl Pharmacol. 2003 Jul 1;190(1):1-8. doi: 10.1016/s0041-008x(03)00152-2.
3
[A preliminary study on alternation of generations of Cordyceps sinensis (Berkey) Sacc].[冬虫夏草（伯克）萨卡世代交替的初步研究]
Zhongguo Zhong Yao Za Zhi. 1998 Apr;23(4):210-2, 254.
4
5
Protein constituent contributes to the hypotensive and vasorelaxant activities of Cordyceps sinensis.蛋白质成分对冬虫夏草的降压和血管舒张活性有贡献。
Life Sci. 2000 Feb 25;66(14):1369-76. doi: 10.1016/s0024-3205(00)00445-8.
6
Antitumor sterols from the mycelia of Cordyceps sinensis.来自中华虫草菌菌丝体的抗肿瘤甾醇。
Phytochemistry. 1999 Aug;51(7):891-8. doi: 10.1016/s0031-9422(99)00128-4.
7
Effects of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells.冬虫夏草水溶性提取物对培养的大鼠肾上腺皮质细胞类固醇生成及脂滴包膜形态的影响。
J Cell Biochem. 1998 Jun 15;69(4):483-9. doi: 10.1002/(sici)1097-4644(19980615)69:4<483::aid-jcb9>3.0.co;2-j.
8
9
Cordyceps sinensis as an immunomodulatory agent.冬虫夏草作为一种免疫调节剂。
Am J Chin Med. 1996;24(2):111-25. doi: 10.1142/S0192415X96000165.
10
Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse.
Jpn J Pharmacol. 1996 Jan;70(1):85-8. doi: 10.1254/jjp.70.85.
Zotero 插件