Ramavat Piyush Rameshchandra, Ramavat Manish Rameshchandra, Ghugare Balaji Wasudeo, Vaishnav Rohini G, Joshi Manjiri Uttam
Senior Resident, Department of Ophthalmology, R.M.L. Hospital , New Delhi, India .
J Clin Diagn Res. 2013 Jul;7(7):1387-90. doi: 10.7860/JCDR/2013/5259.3146. Epub 2013 Jun 1.
Diabetic Retinopathy (DR) can be defined as a damage which is caused to microvasculature in the retina by prolonged hyperglycaemia. Various studies have been conducted in south India, to find out prevalence of DR. It remains a less explored domain among type 2 diabetic patients in western India.
(1) To assess prevalence of diabetic retinopathy in type 2 DM in western Indian population. and (2) To find out effect of duration of diabetes on severity of DR in this population.
A hospital - based, cross - sectional study.
A total of 168 patients with type 2 DM underwent detailed opthalmoscopic examinations for DR. The ETDRS classification was followed to categorize retinopathy in different stages.
We observed that overall, prevalence of DR in type 2 patients of western India was 33.9%. Prevalences of non-proliferative DR and proliferative DR were 25.5% and 8.33% respectively. Statistically significant differences (p value<0.05) were observed between prevalences of DR in each group of patients which was classified, and duration of diabetes. Prevalence of CSME (clinically significant macular oedema) was 6.5%. Associated hypertension showed a statistically significant (p value<0.05%), higher prevalence of DR.
This study concluded that prevalence of DR in type 2 DM patients of western India was 33.9% and that it increased with duration of diabetes. Associated hypertension is a risk factor for development of DR. It was further noted that proliferative DR was prevalent only after having diabetes for 11 years.
糖尿病视网膜病变(DR)可定义为长期高血糖对视网膜微血管造成的损害。印度南部已开展了多项研究以查明DR的患病率。在印度西部,2型糖尿病患者中该领域的研究仍较少。
(1)评估印度西部人群中2型糖尿病患者糖尿病视网膜病变的患病率。(2)查明糖尿病病程对该人群中DR严重程度的影响。
一项基于医院的横断面研究。
共168例2型糖尿病患者接受了详细的眼底镜检查以诊断DR。采用ETDRS分类法对不同阶段的视网膜病变进行分类。
我们观察到,总体而言,印度西部2型患者中DR的患病率为33.9%。非增殖性DR和增殖性DR的患病率分别为25.5%和8.33%。在按糖尿病病程分类的每组患者中,DR患病率之间存在统计学显著差异(p值<0.05)。临床显著性黄斑水肿(CSME)的患病率为6.5%。合并高血压的患者DR患病率具有统计学显著性(p值<0.05%)且更高。
本研究得出结论,印度西部2型糖尿病患者中DR的患病率为33.9%,且随糖尿病病程增加。合并高血压是DR发生的一个危险因素。还进一步注意到,增殖性DR仅在患糖尿病11年后才普遍存在。