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Borrelia burgdorferi HtrA may promote dissemination and irritation.

作者信息

Gherardini Frank C

机构信息

Laboratory of Zoonotic Pathogens, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, Hamilton, MT, 59840, USA; National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, 59840, USA.

出版信息

Mol Microbiol. 2013 Oct;90(2):209-13. doi: 10.1111/mmi.12390. Epub 2013 Sep 16.

DOI:10.1111/mmi.12390
PMID:23998919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4260139/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca4f/4260139/ba3a2f86bc67/mmi0090-0209-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca4f/4260139/ba3a2f86bc67/mmi0090-0209-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca4f/4260139/ba3a2f86bc67/mmi0090-0209-f1.jpg

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Borrelia burgdorferi HtrA may promote dissemination and irritation.伯氏疏螺旋体HtrA可能促进传播和炎症。
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Borrelia burgdorferi BbHtrA degrades host ECM proteins and stimulates release of inflammatory cytokines in vitro.伯氏疏螺旋体 BbHtrA 降解宿主细胞外基质蛋白并刺激体外炎症细胞因子的释放。
Mol Microbiol. 2013 Oct;90(2):241-51. doi: 10.1111/mmi.12377. Epub 2013 Sep 16.
2
Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity.莱姆病螺旋体具有一种聚集蛋白聚糖结合蛋白酶,具有聚集蛋白聚糖酶活性。
Mol Microbiol. 2013 Oct;90(2):228-40. doi: 10.1111/mmi.12276. Epub 2013 Jun 10.
3
Proteases in Mycobacterium tuberculosis pathogenesis: potential as drug targets.
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Front Pharmacol. 2022 Nov 24;13:1040039. doi: 10.3389/fphar.2022.1040039. eCollection 2022.
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Application of biophysical methods for improved protein production and characterization: A case study on an high-temperature requirement A-family bacterial protease.应用生物物理方法提高蛋白质生产和表征:以一种高温需求 A 家族细菌蛋白酶为例。
Protein Sci. 2022 Dec;31(12):e4498. doi: 10.1002/pro.4498.
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BB0761, a MepM homolog, contributes to Borrelia burgdorferi cell division and mammalian infectivity.BB0761,一种 MepM 同源物,有助于伯氏疏螺旋体的细胞分裂和哺乳动物的感染性。
Mol Microbiol. 2022 Jun;117(6):1405-1418. doi: 10.1111/mmi.14916. Epub 2022 May 16.
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Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatment Lyme Disease Syndromes.伯氏疏螺旋体在莱姆病和治疗后莱姆病综合征中的抗微生物药物耐受持久存在。
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