Niedziela Natalia, Adamczyk-Sowa Monika, Pierzchała Krystyna
Department of Neurology, Medical University of Silesia , Zabrze , Poland.
Int J Neurosci. 2014 May;124(5):322-30. doi: 10.3109/00207454.2013.840618. Epub 2013 Oct 4.
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system mainly affecting young adults. The aim of this paper is to review the literature concentrating the main national MS registries in selected countries of the world. We performed a systematic review to determine the MS epidemiology reported on prevalence, incidence, environmental factors, treatment, social consequences of MS and neurological disability or progression among MS-affected people. We got the information on the high-MS prevalence in Sardinia, Sweden or Sicily and on the effects of MS treatment in United States of America, Italy or Germany. We emphasized environmental factors taking into account as MS risk factors. We concluded that there were many descriptions of MS status in particular countries, but they were often insufficiently detailed and not uniform enough to compare it. The paper indicated an importance of the MS epidemiology in the light of the healthcare or quality of life of the MS patients, but further research is needed to optimize this issue.
多发性硬化症（MS）是一种主要影响年轻人的中枢神经系统慢性炎症性自身免疫疾病。本文旨在回顾聚焦世界上选定国家主要全国性MS登记处的文献。我们进行了一项系统综述，以确定所报告的MS流行病学情况，包括患病率、发病率、环境因素、治疗、MS的社会后果以及MS患者的神经功能残疾或病情进展。我们获取了关于撒丁岛、瑞典或西西里岛MS高患病率以及美国、意大利或德国MS治疗效果的信息。我们强调了作为MS风险因素的环境因素。我们得出结论，特定国家有许多关于MS状况的描述，但往往不够详细且不够统一，难以进行比较。鉴于MS患者的医疗保健或生活质量，本文指出了MS流行病学的重要性，但需要进一步研究以优化这一问题。
