Tülek Zeliha, Polat Cansu, Kürtüncü Murat, Eraksoy Mefkure
İstanbul University Florence Nightingale Faculty of Nursing, İstanbul, Turkey.
Department of Neurology, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.
Noro Psikiyatr Ars. 2017 Dec;54(4):328-333. doi: 10.5152/npa.2016.16976. Epub 2016 Apr 26.
Multiple sclerosis (MS) is a disease that causes different symptoms in each attack and has an individual-specific course. Detailed questioning and recording of MS symptoms is important for developing a management plan for individual-specific symptoms. The present study was planned to evaluate the validity and reliability of the Turkish version of "Multiple Sclerosis-Related Symptom Checklist" (MS-RS), which has been developed for patients to personally follow-up the symptoms they experience.
The study was conducted in the outpatient MS clinic of the Istanbul University Istanbul Faculty of Medicine between January and October 2013 and included a sample group of 148 patients who were aged >18 years, could easily communicate, had a definite diagnosis of MS, and had no other medical problems besides MS. The data were collected using patient information forms, including sociodemographic and MS-RS forms. To assess the linguistic validity, the Likert-type scale with 26 items was first applied to a group of 30 patients. Confirmatory factor analysis was used to test the construct validity. Furthermore, the correlation of the scale with the Expanded Disability Status Scale (EDSS), Hospital Anxiety and Depression Scale (HADS), Mini-Mental Status Evaluation (MMSE) scale, and Multiple Sclerosis Quality of Life Scale-54 (MSQL-54) was evaluated.
The scale comprised five factors with factor loading values between 0.39 and 0.86. The item-total correlation coefficients revealed values of 0.27-0.88. The Cronbach's alpha reliability coefficient for the whole scale was determined to be 0.89 and for the subscales to be 0.60-0.85. The test-retest analysis revealed no difference between the scale and its subscales in terms of invariance with time (p>0.05). Moreover, MS-RS was significantly correlated with EDSS, HADS, MMSE, and MSQL-54.
The Turkish version of MS-RS is a valid and reliable scale that can be used in the Turkish population.
多发性硬化症（MS）是一种每次发作都会引发不同症状且病程因人而异的疾病。详细询问并记录MS症状对于制定针对个体特定症状的管理计划至关重要。本研究旨在评估“多发性硬化症相关症状清单”（MS-RS）土耳其语版本的有效性和可靠性，该清单是为患者个人跟踪其所经历的症状而开发的。
该研究于2013年1月至10月在伊斯坦布尔大学伊斯坦布尔医学院的门诊MS诊所进行，纳入了148名年龄大于18岁、沟通顺畅、确诊为MS且除MS外无其他医疗问题的患者作为样本组。数据通过患者信息表收集，包括社会人口统计学和MS-RS表格。为评估语言有效性，首先将包含26个条目的李克特式量表应用于30名患者组成的小组。采用验证性因素分析来检验结构效度。此外，还评估了该量表与扩展残疾状态量表（EDSS）、医院焦虑抑郁量表（HADS）、简易精神状态检查表（MMSE）量表以及多发性硬化症生活质量量表-54（MSQL-54）之间的相关性。
该量表由五个因素组成，因素负荷值在0.39至0.86之间。项目-总分相关系数显示为0.27 - 0.88。整个量表的克朗巴哈α信度系数确定为0.89，各子量表的信度系数为0.60 - 0.85。重测分析表明，该量表及其子量表在随时间的不变性方面没有差异（p>0.05）。此外，MS-RS与EDSS、HADS、MMSE和MSQL-54显著相关。
MS-RS的土耳其语版本是一个有效且可靠的量表，可用于土耳其人群。
