Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
Molecules. 2013 Aug 30;18(9):10465-83. doi: 10.3390/molecules180910465.
Swietenia macrophylla King (Meliaceae) is an endangered and medicinally important plant indigenous to tropical and subtropical regions of the World. S. macrophylla has been widely used in folk medicine to treat various diseases. The review reveals that limonoids and its derivatives are the major constituents of S. macrophylla. There are several data in the literature indicating a great variety of pharmacological activities of S. macrophylla, which exhibits antimicrobial, anti-inflammatory, antioxidant effects, antimutagenic, anticancer, antitumor and antidiabetic activities. Various other activities like anti-nociceptive, hypolipidemic, antidiarrhoeal, anti-infective, antiviral, antimalarial, acaricidal, antifeedant and heavy metal phytoremediation activity have also been reported. In view of the immense medicinal importance of S. macrophylla, this review aimed at compiling all currently available information on its ethnomedicinal uses, phytochemistry and biological activities of S. macrophylla, showing its importance.
巨丝葵（梧桐科）是一种濒危的药用植物，原产于世界热带和亚热带地区。巨丝葵在民间医学中被广泛用于治疗各种疾病。综述表明，柠檬苦素及其衍生物是巨丝葵的主要成分。文献中有多项数据表明，巨丝葵具有多种药理活性，具有抗菌、抗炎、抗氧化作用，具有抗突变、抗癌、抗肿瘤和抗糖尿病作用。还报道了其他各种活性，如抗伤害感受、降血脂、抗腹泻、抗感染、抗病毒、抗疟原虫、杀螨、抗食和重金属植物修复活性。鉴于巨丝葵具有巨大的药用重要性，本综述旨在汇编有关其在民族医学中的用途、巨丝葵的植物化学和生物活性的所有现有信息，以展示其重要性。
