: 民族药用用途、植物化学和药理学的深入了解。
: An Insight into Ethnomedicinal Uses, Phytochemistry, and Pharmacology.
机构信息
Department of Chemistry, Mohanlal Sukhadia University, Udaipur-313001, India.
出版信息
Comb Chem High Throughput Screen. 2024;27(1):2-39. doi: 10.2174/1386207326666230426093315.
BACKGROUND
(guava) is widely distributed in tropical and subtropical regions and adapted to various environmental conditions. Guava is an important economic fruit widely used as food and folk medicine. It contains flavonoids, alkaloids, tannins, triterpenoids, reducing sugars, essential oils, carotenoids, polyphenols, etc. The presence of triterpenoid acids such as guavacoumaric, ursolic, jacoumaric, guajavanoic, guavenoic, and Asiatic acids helps to develop novel drugs against various diseases. It is used traditionally for medicinal purposes, mainly for antioxidant, antimicrobial, antispasmodic, antidiabetic, anticancer, antiallergy, anti-inflammatory, and hepato-protective properties.
OBJECTIVE
The systematic literature study aims to summarize its botanical description, phytochemicals, pharmacological activities, and clinical trials. This review focuses on the plant's chemical composition and scientific approaches to human welfare.
METHODS
A systematic literature search was done on through previous literature and online databases such as Google Scholar, Pubmed, Science Direct, etc., to explain its ethnomedicinal uses, phytochemistry, and pharmacological applications.
RESULTS
Previous literature studies of suggest it can serve as antioxidant, antimicrobial, antispasmodic, antidiabetic, anticancer, anti-allergy, anti-inflammatory, and hepatoprotective effects. Successful clinical trials performed on the plant extracts against infantile rotaviral enteritis and infectious gastroenteritis showed future directions to work with the plant for clinical applications.
CONCLUSION
In this review, an attempt is made to show all literature studied, especially in phytochemistry, pharmacology, clinical trials and uses as traditional folk medicine around the world. The leaves have been used by folklore over the years to treat various ailments such as skin ulcers, diarrhoea, vaginal irritation, cough, conjunctivitis, etc. Further studies are required to explore more therapeutic remedies and to develop new medicines for future perspectives.
背景
（番石榴）广泛分布于热带和亚热带地区，能适应各种环境条件。番石榴是一种重要的经济水果，广泛用作食品和民间药物。它含有类黄酮、生物碱、单宁、三萜、还原糖、精油、类胡萝卜素、多酚等。番石榴酸、熊果酸、齐墩果酸、羽扇豆酸、乌索酸和齐墩果酸等三萜酸的存在有助于开发针对各种疾病的新型药物。它在传统上被用于药用，主要具有抗氧化、抗菌、抗痉挛、抗糖尿病、抗癌、抗过敏、抗炎和保肝作用。
目的
系统文献研究旨在总结其植物描述、植物化学、药理活性和临床试验。本综述重点介绍了植物的化学成分和对人类福利的科学方法。
方法
通过先前的文献和在线数据库（如 Google Scholar、Pubmed、Science Direct 等）进行系统的文献检索，解释其民族医学用途、植物化学和药理学应用。
结果
先前对番石榴的文献研究表明，它具有抗氧化、抗菌、抗痉挛、抗糖尿病、抗癌、抗过敏、抗炎和保肝作用。对植物提取物治疗婴幼儿轮状病毒肠炎和传染性胃肠炎的成功临床试验表明，未来可以将该植物用于临床应用。
结论
在本综述中，我们试图展示所有已研究的文献，特别是在植物化学、药理学、临床试验和作为世界各地传统民间医学的用途方面。多年来，民间一直用叶子来治疗各种疾病，如皮肤溃疡、腹泻、阴道刺激、咳嗽、结膜炎等。需要进一步研究以探索更多的治疗方法，并为未来开发新药。
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