Horita H, Nozaki H, Hamano S, Aihara T
Division of Neurology, Children's Medical Center, Saitama.
No To Hattatsu. 1990 Jul;22(4):341-8.
Single photon emission computed tomography (SPECT) of the brain using N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) was performed in 11 children with port wine stain on the face or head, aged 1.0-14.2 years at investigation. Four cases without neurologic symptoms had no specific abnormality on SPECT and X-ray computed tomography (CT). In 4 cases of so-called Sturge-Weber syndrome with developmental quotients (DQ) or intelligence quotients (IQ) more than 80 and the neurologic symptoms consisting of seizures and hemiplegia, SPECT showed localized reduction of IMP accumulation, and CT exhibited calcification, atrophy and enhancement in 2 cases of 3 with contrast medium infusion in the same areas. In 3 cases with DQ of 50-60 and severer neurologic symptoms, SPECT showed diffuse reduction or defect of IMP accumulation in the ipsilateral hemisphere, and CT exhibited remarkable atrophy, calcifications and enhancement in 2 cases with contrast medium infusion in the same hemisphere. In one case with severe neurologic symptoms, SPECT performed at an early stage showed high IMP accumulation in the ipsilateral hemisphere.
对11例面部或头部患有葡萄酒色斑的儿童进行了单光子发射计算机断层扫描（SPECT），这些儿童在检查时年龄为1.0至14.2岁，使用N-异丙基-p-[123I]碘安非他明（123I-IMP）对脑部进行扫描。4例无神经症状的患儿在SPECT和X线计算机断层扫描（CT）上未发现特异性异常。在4例所谓的斯特奇-韦伯综合征患儿中，其发育商（DQ）或智商（IQ）超过80，神经症状包括癫痫发作和偏瘫，SPECT显示IMP摄取局部减少，在3例中的2例中，CT显示在相同区域注入造影剂后出现钙化、萎缩和强化。在3例DQ为50 - 60且神经症状较重的患儿中，SPECT显示同侧半球IMP摄取弥漫性减少或缺失，在2例中，CT显示在同侧半球注入造影剂后出现明显萎缩、钙化和强化。在1例神经症状严重的患儿中，早期进行的SPECT显示同侧半球IMP摄取增高。
