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杂交主动脉弓分支重建术联合分期腔内修复治疗 DeBakey Ⅰ型主动脉夹层。

Hybrid aortic arch debranching with staged endovascular completion in DeBakey type I aortic dissection.

机构信息

Department of Cardiovascular Disease, Città di Lecce Hospital, GVM Research and Care, Strada Provinciale per Arnesano, Lecce, Italy.

出版信息

Ann Thorac Surg. 2010 Dec;90(6):1847-53. doi: 10.1016/j.athoracsur.2010.07.077.

Abstract

BACKGROUND

We assess midterm results of a hybrid approach to DeBakey type I aortic dissection using a new multibranched Dacron graft to create, by relocation of the inflow openings to the arch vessels toward the aortic root, a new aortic arch for an easier and safer second-staged endovascular stent grafting of the distal thoracic aorta.

METHODS

From March 2006 to July 2008 24 patients with DeBakey type I aortic dissection underwent ascending aorta and aortic arch replacement with debranching of epiaortic vessels using a new prosthesis to create an optimal landing zone for possible subsequent endovascular stent grafting of the distal thoracic aorta. Fifteen patients, who postoperatively presented a residual patent distal false lumen, underwent a successful second-stage endovascular stent-graft implantation.

RESULTS

One patient died after the surgical stage while there was no death after the endovascular stage with hospital mortality of 4.2%. Follow-up confirmed complete thrombosis of the residual distal false lumen in 95.6% and partial thrombosis in 4.4% of patients with no evidence of endoleaks in the cases that required the endovascular procedure. Overall actuarial survival at 28 months is 92.1% ± 7.9% with 100% freedom from reoperation.

CONCLUSIONS

Hybrid treatment of DeBakey type I aortic dissection with aortic arch debranching, using a new multibranched prosthesis (Lupiae Graft; Vascutek Terumo Inc, Scotland, United Kingdom) is confirmed to facilitate the subsequent endovascular completion. Midterm results in terms of survival and distal false lumen thrombosis are satisfactory. Further study of this operation is warranted to confirm the effectiveness and the durability of this approach.

摘要

背景

我们评估了一种使用新型多分支涤纶移植物的杂交方法治疗 DeBakey Ⅰ型主动脉夹层的中期结果,通过将流入开口重新定位到弓状血管靠近主动脉根部,为更容易和更安全的第二期胸主动脉腔内支架移植术创建一个新的主动脉弓。

方法

2006 年 3 月至 2008 年 7 月,24 例 DeBakey Ⅰ型主动脉夹层患者接受升主动脉和主动脉弓置换术,使用一种新的假体分支血管,为可能随后进行的胸主动脉远端腔内支架移植术创建一个最佳的着陆区。15 例患者术后存在残余的胸主动脉远端假腔开放,成功进行了第二期腔内支架移植术。

结果

1 例患者在手术阶段后死亡,而在腔内阶段后无死亡,院内死亡率为 4.2%。随访证实,95.6%的患者残余的胸主动脉远端假腔完全血栓形成,4.4%的患者部分血栓形成,需要腔内手术的病例均无内漏证据。28 个月时的总体生存累积生存率为 92.1%±7.9%,再次手术的无复发率为 100%。

结论

使用新型多分支假体(Lupiae 移植物;Vascutek Terumo Inc,苏格兰,联合王国)进行主动脉弓分支的 DeBakey Ⅰ型主动脉夹层的杂交治疗,被证实可以促进随后的腔内完成。在生存和胸主动脉远端假腔血栓形成方面,中期结果令人满意。需要进一步研究这种手术以确认这种方法的有效性和耐久性。

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