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伴有广泛血栓形成的肾恶性孤立性纤维性肿瘤:一例报告并文献复习

Malignant solitary fibrous tumour of the kidney with an extensive thrombus: A case report and review of the literature.

作者信息

Couture Félix, Legault Benjamin, Ekindi Nadia, Noel-Lamy Maxime, Pavic Michel, Richard Patrick O

机构信息

Department of Surgery, Division of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.

Department of Pathology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.

出版信息

Urol Case Rep. 2019 Jul 29;26:100974. doi: 10.1016/j.eucr.2019.100974. eCollection 2019 Sep.

Abstract

Solitary fibrous tumours (SFTs) are neoplasms originating from mesenchymal cells, usually found in lung pleura. Extrapleuritic lesions are extremely rare, with about 60 cases of SFTs of the kidney available in the English literature. We report here the first case of a malignant SFT of the kidney presenting with an extensive vascular thrombus extending to the right atrium with associated pulmonary emboli. We describe management, pathological assessment, as well as radiological and clinical evolution. Our report provides a first therapeutic approach to a critical presentation of a rare pathology, which should help guide management of such disease in future cases.

摘要

孤立性纤维性肿瘤(SFTs)是起源于间充质细胞的肿瘤,通常见于肺胸膜。胸膜外病变极为罕见,英文文献中仅有约60例肾脏SFTs的报道。我们在此报告首例肾脏恶性SFT,伴有广泛的血管血栓延伸至右心房并伴有肺栓塞。我们描述了治疗、病理评估以及影像学和临床演变情况。我们的报告为这种罕见病理的危急表现提供了首个治疗方法,这应有助于指导未来此类疾病的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dd3/6677885/be005cfa387e/gr1.jpg

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