Khosravi Samani Mahmoud, Jalali Farzad, Seyyed Ahadi Seyyed Masud, Hoseini Seyyed Reza, Dabbagh Sattari Farhad
Department of Periodontics, Dental School, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2013 Spring;4(2):667-71.
Periodontitis is common in adults and cardiovascular diseases (CVD) are the most common cause of adult death in the world. This study aimed to investigate the relationship between CVD and periodontitis.
Sixty patients with myocardial infarction (MI) as case and 63 subjects with periodontitis without MI as control were studied. Periodontitis was assessed according to Ramfjord periodontal diseases index and the number of missing teeth besides classic risk factors of MI were recorded.
The patients who lost more than 10 teeth were at more risk of myocardial infarction (OR=2.73). There was a significant relationship between mean attachment loss and MI (p=0.0001). There was also a relation between attachment loss more than 3 mm and MI with OR of 4. Significant difference between mean PDI (periodontal disease index) was seen in case and control groups (p=0.0001). Subjects with PDI>4 were at more risk of periodontal diseases (OR=7.87).
The results show the presence of significant relation between periodontitis and MI which could serve as an alarm to treat periodontitis carefully.
牙周炎在成年人中很常见,而心血管疾病(CVD)是全球成年人死亡的最常见原因。本研究旨在调查心血管疾病与牙周炎之间的关系。
以60例心肌梗死(MI)患者为病例组,63例无心肌梗死的牙周炎患者为对照组进行研究。根据Ramfjord牙周疾病指数评估牙周炎情况,并记录除心肌梗死经典危险因素外的缺失牙数量。
失牙超过10颗的患者发生心肌梗死的风险更高(OR=2.73)。平均附着丧失与心肌梗死之间存在显著关系(p=0.0001)。附着丧失超过3mm与心肌梗死之间也存在关联,OR为4。病例组和对照组的平均牙周疾病指数(PDI)存在显著差异(p=0.0001)。PDI>4的受试者患牙周疾病的风险更高(OR=7.87)。
结果表明牙周炎与心肌梗死之间存在显著关系,这可作为一个警示,提醒要谨慎治疗牙周炎。