Department of Prosthodontics, Medical University of Warsaw, 02-097 Warsaw, Poland.
Department of Periodontal and Oral Mucosa Diseases, Medical University of Warsaw, 02-097 Warsaw, Poland.
Int J Environ Res Public Health. 2022 Jun 14;19(12):7265. doi: 10.3390/ijerph19127265.
According to recent scientific consensus, there is an increasing amount of evidence on the correlation between oral health and cardiovascular disease morbidity. The aim of the present study was to investigate the number of missing teeth, the presence of residual roots with necrotic pulp and teeth with caries, the type of teeth deficiencies, and periodontal status in patients after myocardial infarction (MI). A total of 151 patients after MI and 160 randomly selected controls without history of MI were enrolled in the study. Epidemiological data were collected, and dental examination was performed. Findings showed significantly more women, subjects with lower level of education, lower income, higher percentage of nicotine addiction, more frequent presence of arterial hypertension, diabetes, and obesity than in the study group. Moreover, oral status of the subjects who suffered from MI was inferior to the control group. An average patient from the study group had 11 missing teeth, when compared to four missing teeth in an average control subject (p < 0.0001). The majority of patients in the control group had occlusal contacts in intercuspal position in premolars and molars (group A), in contrast to the patients after MI, who had at least one missing supporting zone (group B) (p < 0.0001). Severe periodontitis was found in 50.3% of tests and in 30.4% of controls (p < 0.0001). A correlation was found between the edentulousness and the risk of myocardial infarction after adjusting for other known risk factors of cardiovascular diseases (OR = 3.8; 95% CI = 3.01−7.21; p < 0.0001). This case−control study showed that MI patients had more missing teeth, more residual roots with necrotic pulp, much higher incidence of edentulism and occlusal contacts in intercuspal position in fewer than four occlusal supporting zones, as well as worse periodontal status when compared to healthy subjects without a history of MI. Due to the methodology of unmatched controls, the presented results must be interpreted with caution.
根据最近的科学共识,越来越多的证据表明口腔健康与心血管疾病发病率之间存在关联。本研究旨在调查心肌梗死(MI)患者的失牙数量、存在坏死牙髓和龋齿的残根以及牙齿缺失类型以及牙周状况。共有 151 名 MI 后患者和 160 名随机选择的无 MI 病史的对照组患者纳入研究。收集了流行病学数据并进行了口腔检查。结果显示,女性、受教育程度较低、收入较低、尼古丁成瘾率较高、动脉高血压、糖尿病和肥胖更为常见的患者比例高于研究组。此外,MI 组患者的口腔状况劣于对照组。研究组的平均患者缺失 11 颗牙齿,而对照组的平均患者缺失 4 颗牙齿(p<0.0001)。对照组的大多数患者在磨牙和前磨牙的正中位有咬合接触(A 组),而 MI 后患者至少有一个缺失的支持区(B 组)(p<0.0001)。50.3%的测试中发现严重牙周炎,30.4%的对照组中发现严重牙周炎(p<0.0001)。在校正其他已知心血管疾病危险因素后,发现无牙与心肌梗死的风险之间存在相关性(OR=3.8;95%CI=3.01−7.21;p<0.0001)。这项病例对照研究表明,与无 MI 病史的健康受试者相比,MI 患者失牙更多,残根更多,坏死牙髓更多,牙列缺失发生率更高,少于四个咬合支持区的磨牙和前磨牙在正中位有咬合接触,以及牙周状况更差。由于对照非匹配的方法学,必须谨慎解释所呈现的结果。