Alavi Seyed-Mohammad, Nadimi Mohammad, Zamani Gholam Abbas
Jundishapur Infectious and Tropical Diseases Research Center, Jundishapur University of Medical Sciences Ahvaz, Iran.
Caspian J Intern Med. 2013 Summer;4(3):722-6.
Although infectious diseases are the most common sources for the fever of unknown origin (FUO), but the spectrum of infectious diseases is changing overtime. The purpose of the study was to define the clinical spectrum and changing the pattern of FUO.
This existing data based study was undertaken from 2007 to 2011. One hundred-six patients fulfilling the modified criteria for FUO referred in a teaching hospital in Ahvaz were enrolled for analysis. The data extracted from the patient's medical files and etiologic agents caused FUO to be assessed.
Infections were the most common cause of FUO in 48.4% of the patients. Among the infections, the most important causes of FUO were represented by extra-pulmonary tuberculosis 15 (31.9%), osteomyelitis 10 (21.3%) and abdominal abscesses 6 (12.8%).
The pattern of FUO in the region is thought to be changed to extra pulmonary TB and osteomyelitis. Tuberculosis is still the leading cause of FUO in our region.
尽管传染病是不明原因发热(FUO)最常见的病因,但传染病谱随时间推移在发生变化。本研究的目的是明确FUO的临床谱及其变化模式。
本研究基于现有数据,于2007年至2011年开展。纳入了阿瓦士一家教学医院收治的106例符合FUO修订标准的患者进行分析。从患者病历中提取数据,并对导致FUO的病原体进行评估。
感染是48.4%患者FUO的最常见病因。在感染中,FUO的最重要病因是肺外结核15例(31.9%)、骨髓炎10例(21.3%)和腹腔脓肿6例(12.8%)。
该地区FUO的模式被认为已转变为肺外结核和骨髓炎。结核病仍是我们地区FUO的主要病因。