小儿胃肠道疾病干细胞治疗的最新进展。
Recent achievements in stem cell therapy for pediatric gastrointestinal tract disease.
作者信息
Bae Sun Hwan
机构信息
Department of Pediatrics, School of Medicine, Konkuk University, Seoul, Korea.
出版信息
Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):10-6. doi: 10.5223/pghn.2013.16.1.10. Epub 2013 Mar 31.
Abstract
The field of stem cell research has been rapidly expanding. Although the clinical usefulness of research remains to be ascertained through human trials, the use of stem cells as a therapeutic option for currently disabling diseases holds fascinating potential. Many pediatric gastrointestinal tract diseases have defect in enterocytes, enteric nervous system cells, smooth muscles, and interstitial cells of Cajal. Various kinds of therapeutic trials using stem cells could be applied to these diseases. This review article focuses on the recent achievements in stem cell applications for pediatric gastrointestinal tract diseases.
摘要
干细胞研究领域一直在迅速扩展。尽管研究的临床实用性仍有待通过人体试验来确定，但将干细胞用作当前致残性疾病的一种治疗选择具有迷人的潜力。许多儿科胃肠道疾病在肠上皮细胞、肠神经系统细胞、平滑肌和 Cajal 间质细胞方面存在缺陷。各种使用干细胞的治疗试验可应用于这些疾病。这篇综述文章重点关注干细胞在儿科胃肠道疾病应用方面的最新成果。
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