功能性消化不良患者胆囊运动功能的超声分析
Ultrasonography analysis of gallbladder motility in patients with functional dyspepsia.
作者信息
Milinić Nikola, Filipovic Branka, Lukić Tamara, Marković Olivera, Milisavljević Nemanja, Gajić Milan, Filipovic Branislav
机构信息
Faculty of Medicine, University of Belgrade, Serbia; Department of Gastroenterohepatology Clinical and Hospital Center "Bezanijska Kosa," Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Serbia; Department of Gastroenterohepatology Clinical and Hospital Center "Bezanijska Kosa," Belgrade, Serbia.
出版信息
Eur J Intern Med. 2014 Feb;25(2):156-9. doi: 10.1016/j.ejim.2013.08.699. Epub 2013 Sep 4.
BACKGROUND
Gallbladder motility has been studied in patients with functional gastrointestinal disorders, such as functional dyspepsia, irritable bowel syndrome and biliary disorders without gallstones and results of these observations are often inconclusive and conflicting.
METHODS
The investigation was performed on 180 therapy-naïve newly diagnosed patients with functional dyspepsia (97 females and 83 males), aged 20-79 in which we have investigate ultrasonographically parameters of gallbladder motility.
RESULTS
Bonferroni post hoc correction stressed that fasting gallbladder volume and ejection fraction were significantly distorted in individuals with postprandial distress syndrome, although, the residual gallbladder volume was significantly lower in patients with epigastric pain syndrome comparing with other examinees. Ejection fraction of the gallbladder negatively correlated with body mass index.
CONCLUSION
The impaired contractibility of the gall bladder in patients with functional dyspepsia, based on the results of this study, is illustrated by the changes in the ejection fraction, which was more pronounced in patients with the postprandial distress syndrome.
背景
已对功能性胃肠疾病患者的胆囊运动功能进行了研究，如功能性消化不良、肠易激综合征以及无胆结石的胆道疾病，而这些观察结果往往缺乏定论且相互矛盾。
方法
对180例初诊的未经治疗的功能性消化不良患者（97例女性，83例男性）进行了调查，这些患者年龄在20至79岁之间，我们通过超声检查了胆囊运动功能参数。
结果
Bonferroni事后检验强调，餐后不适综合征患者的空腹胆囊容积和射血分数明显异常，不过，与其他受检者相比，上腹部疼痛综合征患者的残余胆囊容积明显更低。胆囊射血分数与体重指数呈负相关。
结论
基于本研究结果，功能性消化不良患者胆囊收缩功能受损表现为射血分数的变化，这在餐后不适综合征患者中更为明显。
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