De León-Rodríguez Luis M, Lubag Angelo J M, López Jorge A, Andreu-de-Riquer Gabriel, Alvarado-Monzón José C, Sherry A Dean
Departamento de Química, Universidad de Guanajuato, Cerro de la Venada s/n, Guanajuato, Gto., C.P. 36040, México.
Medchemcomm. 2012 Apr 1;3(4):480-483. doi: 10.1039/C2MD00301E.
A Zn specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn binding agent, the new agent binds to human albumin both in the presence and absence of Zn.
制备并表征了一种含有两个双（3-吡唑基）单元的锌特异性钆喷酸衍生物。与先前报道的锌结合剂不同，这种新型试剂在有锌和无锌的情况下均能与人血清白蛋白结合。
