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Hematological changes in the mice transplanted with methylcholanthrene-induced fibrosarcoma.

作者信息

Higashihara T, Takeshima T, Kuhara T, Tajima M, Tamura H

机构信息

Second Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan.

出版信息

Jikken Dobutsu. 1990 Jul;39(3):407-11. doi: 10.1538/expanim1978.39.3_407.

DOI:10.1538/expanim1978.39.3_407
PMID:2401326
Abstract

Hematological values of the peripheral blood in the mice transplanted with methylcholanthrene-induced fibrosarcoma were examined. Values for red blood cells and platelets reduced after tumor transplantation. Values for white blood cells increased with the percentage of neutrophils being increased significantly. Phagocytic activity of neutrophils from the tumor-bearing mice was not reduced. The cultured fluid of the tumor used in the experiments possessed strong colony stimulating activity to bone marrow cells.

摘要

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