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Progesterone and vitamin d hormone as a biologic treatment of traumatic brain injury in the aged.孕激素和维生素 D 激素作为一种生物疗法治疗老年创伤性脑损伤。
PM R. 2011 Jun;3(6 Suppl 1):S100-10. doi: 10.1016/j.pmrj.2011.03.010.
2
Risk factors analysis on traumatic brain injury prognosis.
Chin Med Sci J. 2011 Jun;26(2):98-102. doi: 10.1016/s1001-9294(11)60027-8.
3
Sex differences for traumatic brain injury outcomes: comment on "Protection from traumatic brain injury in hormonally active women vs men of a similar age".
Arch Surg. 2011 Apr;146(4):442-3. doi: 10.1001/archsurg.2011.34.
4
Progesterone for acute traumatic brain injury.孕酮用于急性创伤性脑损伤。
Cochrane Database Syst Rev. 2011 Jan 19(1):CD008409. doi: 10.1002/14651858.CD008409.pub2.
5
Epidemiology of traumatic brain injury in eastern China, 2004: a prospective large case study.2004年中国东部创伤性脑损伤的流行病学:一项前瞻性大型病例研究。
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6
Traumatic brain injury in older adults: epidemiology, outcomes, and future implications.老年人创伤性脑损伤:流行病学、结局及未来影响
J Am Geriatr Soc. 2006 Oct;54(10):1590-5. doi: 10.1111/j.1532-5415.2006.00894.x.
7
Traumatic brain injury outcomes in pre- and post- menopausal females versus age-matched males.绝经前和绝经后女性与年龄匹配男性的创伤性脑损伤结局
J Neurotrauma. 2006 Feb;23(2):140-8. doi: 10.1089/neu.2006.23.140.
8
A follow-up study of older adults with traumatic brain injury: taking into account decreasing length of stay.对老年创伤性脑损伤患者的随访研究:考虑住院时间的缩短
Arch Phys Med Rehabil. 2006 Jan;87(1):57-62. doi: 10.1016/j.apmr.2005.07.309.
9
Incidence and risk factors of severe traumatic brain injury resulting from road accidents: a population-based study.道路交通事故所致重型颅脑损伤的发病率及危险因素:一项基于人群的研究。
Accid Anal Prev. 2006 Mar;38(2):225-33. doi: 10.1016/j.aap.2005.08.001. Epub 2005 Oct 18.
10
Dementia after traumatic brain injury.创伤性脑损伤后的痴呆症
Int Psychogeriatr. 2005;17 Suppl 1:S93-107. doi: 10.1017/s1041610205001973.

中国的老年创伤性脑损伤

Geriatric Traumatic Brain Injury in China.

作者信息

Zeng Xianwei, Pan Shun, Hu Zhenbo

机构信息

Department of Neurosurgery, Affiliated Hospital of Weifang Medical University, 465 Yuhe Road, WeiFang, 261031 Shandong People's Republic of China.

出版信息

Curr Transl Geriatr Exp Gerontol Rep. 2012 Jun 19;1(3):167-170. doi: 10.1007/s13670-012-0018-1. eCollection 2012.

DOI:10.1007/s13670-012-0018-1
PMID:24014155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3758510/
Abstract

Traumatic brain injury (TBI) is one of the major causes of morbidity and mortality in China. The elderly population has the higher rates of TBI-related hospitalization and death. Traffic accidents are the major cause for TBI in all age groups except in the group of 75 years and older, in which stumbles occurred in nearly half of those who suffered TBI. Older age is known to negatively influence outcome after TBI. To date, investigators have identified a panel of prognostic factors that include initial Glasgow Coma Scale score, comorbidities, cerebrospinal fluid leakage, associated extracranial lesions, and other factors such as cerebral perfusion pressure on recovery after injury. However, these aspects remain understudied in elderly patients with TBI. In the absence of complete clinical data, predicting outcomes and providing good care of the elderly population with TBI remain limited. To address this significant public health issue, a refocusing of research efforts is justified to prevent TBI in this population and to develop unique care strategies for achieving better clinical outcomes of the patients with TBI.

摘要

创伤性脑损伤(TBI)是中国发病和死亡的主要原因之一。老年人群的TBI相关住院率和死亡率较高。交通事故是所有年龄组TBI的主要原因,但75岁及以上年龄组除外,该年龄组近一半的TBI患者是因绊倒所致。众所周知,年龄较大对TBI后的预后有负面影响。迄今为止,研究人员已经确定了一组预后因素,包括初始格拉斯哥昏迷量表评分、合并症、脑脊液漏、相关颅外病变以及其他因素,如损伤后恢复过程中的脑灌注压。然而,这些方面在老年TBI患者中仍研究不足。在缺乏完整临床数据的情况下,预测老年TBI患者的预后并提供良好护理仍存在局限性。为解决这一重大公共卫生问题,有必要重新调整研究重点,以预防该人群发生TBI,并制定独特的护理策略,以改善TBI患者的临床结局。