Zeng Xianwei, Pan Shun, Hu Zhenbo
Department of Neurosurgery, Affiliated Hospital of Weifang Medical University, 465 Yuhe Road, WeiFang, 261031 Shandong People's Republic of China.
Curr Transl Geriatr Exp Gerontol Rep. 2012 Jun 19;1(3):167-170. doi: 10.1007/s13670-012-0018-1. eCollection 2012.
Traumatic brain injury (TBI) is one of the major causes of morbidity and mortality in China. The elderly population has the higher rates of TBI-related hospitalization and death. Traffic accidents are the major cause for TBI in all age groups except in the group of 75 years and older, in which stumbles occurred in nearly half of those who suffered TBI. Older age is known to negatively influence outcome after TBI. To date, investigators have identified a panel of prognostic factors that include initial Glasgow Coma Scale score, comorbidities, cerebrospinal fluid leakage, associated extracranial lesions, and other factors such as cerebral perfusion pressure on recovery after injury. However, these aspects remain understudied in elderly patients with TBI. In the absence of complete clinical data, predicting outcomes and providing good care of the elderly population with TBI remain limited. To address this significant public health issue, a refocusing of research efforts is justified to prevent TBI in this population and to develop unique care strategies for achieving better clinical outcomes of the patients with TBI.
创伤性脑损伤(TBI)是中国发病和死亡的主要原因之一。老年人群的TBI相关住院率和死亡率较高。交通事故是所有年龄组TBI的主要原因,但75岁及以上年龄组除外,该年龄组近一半的TBI患者是因绊倒所致。众所周知,年龄较大对TBI后的预后有负面影响。迄今为止,研究人员已经确定了一组预后因素,包括初始格拉斯哥昏迷量表评分、合并症、脑脊液漏、相关颅外病变以及其他因素,如损伤后恢复过程中的脑灌注压。然而,这些方面在老年TBI患者中仍研究不足。在缺乏完整临床数据的情况下,预测老年TBI患者的预后并提供良好护理仍存在局限性。为解决这一重大公共卫生问题,有必要重新调整研究重点,以预防该人群发生TBI,并制定独特的护理策略,以改善TBI患者的临床结局。