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氧化锌纳米花作为大肠杆菌抗菌剂及无酶葡萄糖传感器的应用。

Applications of ZnO nanoflowers as antimicrobial agents for Escherichia coli and enzyme-free glucose sensor.

作者信息

Umar Ahmad, Chauhan M S, Chauhan S, Kumar R, Sharma P, Tomar Kirti Janghu, Wahab R, Al-Hajry A, Singh Dilbag

机构信息

Promising Centre for Sensors and Electronic Devices, Najran University, Najran 11001, Kingdom of Saudi Arabia.

出版信息

J Biomed Nanotechnol. 2013 Oct;9(10):1794-802. doi: 10.1166/jbn.2013.1751.

Abstract

Well-crystalline ZnO nanoflowers were prepared by a facile solution process and their applications as an antimicrobial agent against Escherichia coli and enzyme-free glucose sensor have been studied. The morphological, structural, compositional, and optical properties of ZnO nanoflowers were characterized by various techniques, which confirmed the well-crystalline wurtzite hexagonal phase. The minimum inhibitory concentration of ZnO nanoflowers for inhibiting the growth of Escherichia coli was found to be 25 microg/ml. ZnO nanoflowers were also tested as an efficient electron mediator for the fabrication of highly sensitive non-enzymatic glucose sensor, which exhibited a high sensitivity of -411 microA M(-1) cm(-2) and detection limit of -1.25 mM with a quick response time of -10.0 s. The presented studies showed that ZnO nanomaterials can be efficiently used as an antimicrobial agent and a highly sensitive non-enzymatic glucose sensor.

摘要

通过简便的溶液法制备了结晶良好的ZnO纳米花,并研究了它们作为抗大肠杆菌抗菌剂和无酶葡萄糖传感器的应用。采用多种技术对ZnO纳米花的形态、结构、组成和光学性质进行了表征,证实其为结晶良好的纤锌矿六方相。发现ZnO纳米花抑制大肠杆菌生长的最低抑菌浓度为25μg/ml。ZnO纳米花还作为一种有效的电子介质用于制备高灵敏度的非酶葡萄糖传感器进行了测试,该传感器具有-411μA M(-1) cm(-2)的高灵敏度、-1.25 mM的检测限和-10.0 s的快速响应时间。所呈现的研究表明,ZnO纳米材料可有效地用作抗菌剂和高灵敏度的非酶葡萄糖传感器。

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