伊朗北部巴博勒地区甲状腺癌的风险因素
Risk factors of thyroid cancer in Babol, Northern Iran.
作者信息
Moazezi Zoleika, Mahmoudi Mahmoud, Yahyahpour Yousef, Alaleh Alireza
机构信息
Department of Internal Medicine, Babol University of Medical Sciences, Babol, Iran.
出版信息
Caspian J Intern Med. 2011 Winter;2(1):171-7.
UNLABELLED
Background : Thyroid cancer is the most common endocrine malignancy. Several risk factors were found to play a role in thyroid cancer. The purpose of the study was to determine the risk factors for thyroid cancer, in Babol, north of Iran.
METHOD
Eighty patients with thyroid cancer were selected as case group and 160 people living in the neighborhood of the patients as control group. Risk factors in both groups were collected and compared. The odds ratio (OR) as well as the marginal logistic regression model were used to estimate the possible risk factors. Result : X-ray exposure, radioactive exposure, family history of thyroid cancer, history of hyperthyroidism, hypothyroidism and thyroid resection were found to be the risk factors of thyroid cancer (p<0.05). Passion exposure, OCP user, history of hysterectomy, history of thyroid nodule were not correlated to thyroid cancer (p>0.05).
CONCLUSION
History of goiter or other benign thyroid diseases are among the thyroid cancer risk factors in some community-based interventions to prevent or treat the disease in early stages are recommended in our region.
未标注
背景：甲状腺癌是最常见的内分泌恶性肿瘤。已发现多种危险因素在甲状腺癌中起作用。本研究的目的是确定伊朗北部巴博勒地区甲状腺癌的危险因素。
方法
选取80例甲状腺癌患者作为病例组，选取居住在患者附近的160人作为对照组。收集并比较两组的危险因素。采用比值比（OR）以及边际逻辑回归模型来估计可能的危险因素。结果：X线照射、放射性暴露、甲状腺癌家族史、甲亢病史、甲减病史和甲状腺切除术被发现是甲状腺癌的危险因素（p<0.05）。激情暴露、口服避孕药使用者、子宫切除术史、甲状腺结节病史与甲状腺癌无关（p>0.05）。
结论
在某些社区干预措施中，甲状腺肿或其他良性甲状腺疾病史属于甲状腺癌的危险因素，建议在我们地区早期预防或治疗该疾病。
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