Department of Acupuncture and Moxibustion, Shanghai Tianshan Hospital of Traditional Chinese Medicine, Shanghai 200051, China.
J Tradit Chin Med. 2013 Jun;33(3):287-93. doi: 10.1016/s0254-6272(13)60166-1.
To explore the effect of electroacupuncture and Chinese kidney-nourishing medicine on insulin (INS), adiponectin (APN), leptin (LEP), and glucolipid metabolism of obese patients with polycystic ovary syndrome (PCOS).
Sixty-seven obese PCOS patients were randomly divided into two groups. Thirty-three patients in the acupuncture-medicine group were treated three times a week with electroacupuncture at the Tianshu (ST 25), Zhongwan (CV 12), Qi-hai (CV 6), Sanyinjiao (SP 6), Geshu (BL 17), and Ciliao (BL 32) acupoints. They also took the Chinese drug, Tiankui capsule, for 3 months as a course of treatment. Point-taking and treatment in the electroacupuncture group of 34 patients was the same as those in the acupuncture-medicine group. We observed and compared the changes in the obesity-related indexes of body weight (BW), body mass index (BMI), and waist-hip ratio (WHR), as well as fasting plasma glucose (FPG), fasting insulin (FINS), APN, and LEP.
BW, BMI, WHR, and FINS decreased and insulin sensitivity index (ISI) and APN were higher in the acupuncture-medicine group than in the electroacupuncture group (P < 0.01). There was no obvious difference in LEP between the two groups (P > 0.05).
Acupuncture combined with medicine is better than just electroacupuncture for obese PCOS patients by improving obesity-related indexes, insulin sensitivity, and APN level. This indicates that acupuncture-medicine therapy is worth clinical popularization.
探讨电针和补肾中药对肥胖型多囊卵巢综合征(PCOS)患者胰岛素(INS)、脂联素(APN)、瘦素(LEP)及糖脂代谢的影响。
将 67 例肥胖型 PCOS 患者随机分为 2 组。针刺组 33 例采用电针天枢(ST25)、中脘(CV12)、气海(CV6)、三阴交(SP6)、膈俞(BL17)、次髎(BL32)等穴,每周 3 次,同时口服天癸胶囊治疗,3 个月为 1 个疗程。针刺组 34 例针刺操作同针刺组,不加电针。观察比较两组患者体重(BW)、体质量指数(BMI)、腰臀比(WHR)等肥胖相关指标以及空腹血糖(FPG)、空腹胰岛素(FINS)、APN、LEP 的变化。
针刺组治疗后 BW、BMI、WHR 下降,胰岛素敏感指数(ISI)升高,APN 升高,FINS 降低,与电针组比较差异有统计学意义(P<0.01)。两组 LEP 比较差异无统计学意义(P>0.05)。
电针联合补肾中药治疗肥胖型 PCOS 患者在改善肥胖相关指标、胰岛素敏感性及 APN 水平方面优于单纯电针,提示针刺联合中药治疗值得临床推广。