Program in Nutritional Sciences, University of Washington, United States.
Appetite. 2013 Dec;71:301-6. doi: 10.1016/j.appet.2013.09.001. Epub 2013 Sep 8.
Using a twin study design, we sought to determine whether an early age at dieting onset is a risk factor for higher adult body mass index (BMI) or use of risky dieting practices, independent of genetic and familial factors.
Female twins ages 18-60 years (N=950) from the University of Washington Twin Registry completed 2 surveys an average of 3 years apart. Analyses of individual twins and within-twin pairs tested associations of self-reported age at dieting onset with (1) adult BMI at baseline, (2) change in BMI between the two surveys and (3) risky dieting behaviors at baseline.
In analyses mimicking studies of unrelated individuals, an earlier age at dieting onset was associated with greater adult BMI (p=0.003), higher Restraint Scale scores (p<0.001), greater use of risky dieting behaviors (p=0.04) and more weight cycling episodes (p<0.001). In within-pair models that control for genetic and familial factors, the only significant association was between an earlier age at dieting onset and more weight cycling episodes (p=0.006).
Underlying genetic and familial factors may influence associations of early dieting with higher adult BMIs and risky dieting practices in women.
本研究采用双胞胎设计,旨在确定节食起始年龄是否是成年后体重指数(BMI)较高或采用危险节食行为的风险因素,而不受遗传和家庭因素的影响。
来自华盛顿大学双胞胎登记处的年龄在 18-60 岁之间的女性双胞胎(N=950)完成了两次调查,两次调查平均间隔 3 年。对个体双胞胎和双胞胎对内部的分析测试了报告的节食起始年龄与(1)基线时成年 BMI,(2)两次调查之间 BMI 的变化以及(3)基线时危险节食行为之间的关联。
在模仿非相关个体研究的分析中,节食起始年龄较早与成年 BMI 较高相关(p=0.003)、节食量表评分较高(p<0.001)、危险节食行为使用较多(p=0.04)和体重循环次数较多(p<0.001)。在控制遗传和家庭因素的双胞胎对内部模型中,唯一显著相关的是节食起始年龄较早与体重循环次数较多(p=0.006)。
潜在的遗传和家庭因素可能会影响早期节食与女性成年 BMI 较高和危险节食行为之间的关联。