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宫腔镜子宫中隔切除术:与中隔大小相关的生殖结局。

Hysteroscopic metroplasty: reproductive outcome in relation to septum size.

机构信息

Department of Obstetrics, Gynecology and Reproductive Biology, S. Orsola Hospital, University Alma Mater Studiorum of Bologna, Massarenti 13, 40138, Bologna, Italy,

出版信息

Arch Gynecol Obstet. 2014 Mar;289(3):671-6. doi: 10.1007/s00404-013-3003-9. Epub 2013 Sep 12.

Abstract

PURPOSE

Our aim is to determine if the reproductive performance after hysteroscopic resection of partial uterine septum was related to septum size.

METHODS

The retrospective and comparative cohort study was conducted in a University-affiliated Hospital. A cohort of 112 non-parous patients was treated for a partial uterine septum. The septum size was evaluated by hysteroscopy and transvaginal 3-dimensional ultrasound. The patients were stratified into two groups: group 1 (85 women) with small partial uterine septum (≤2.5 cm) and group 2 (27 women) with large partial uterine septum (>2.5 cm). They were also divided according to their obstetrics history: 39 infertile women and 73 aborters. All underwent hysteroscopic metroplasty with a resectoscope with an equatorial semicircular loop cutting 0° with monopolar energy. All septa were almost completely removed and no complications occurred.

RESULTS

The two groups of patients with small (group 1) and large (group 2) partial uterine septum were compared in the terms of reproductive history and performance before and after surgery. In the overall population the reproductive performance after surgery is greatly improved. No significant differences in reproductive performance were evident between patients with small and large partial uterine septa. The reproductive performance was also similar in infertile patients and in aborters.

CONCLUSIONS

This study demonstrates that hysteroscopic metroplasty in cases of partial uterine septum and infertility significantly improves the reproductive performance irrespectively of septum size and that reproductive performance is independent from previous obstetrics history.

摘要

目的

我们旨在确定子宫中隔部分切除术的生殖预后是否与中隔大小有关。

方法

这是一项在大学附属医院进行的回顾性和对照队列研究。对 112 名未生育的中隔患者进行了子宫中隔部分切除术。通过宫腔镜和经阴道 3 维超声评估中隔大小。将患者分为两组:组 1(85 名女性)为小的部分子宫中隔(≤2.5cm),组 2(27 名女性)为大的部分子宫中隔(>2.5cm)。根据其产科史也将其分为两组:39 名不孕患者和 73 名流产患者。所有患者均采用带有赤道半圆形切割 0°的单极电切环的宫腔镜进行子宫成形术。所有中隔均被几乎完全切除,且无并发症发生。

结果

在生殖史和手术前后的生殖表现方面,对小(组 1)和大(组 2)部分子宫中隔患者进行了比较。在总体人群中,手术后的生殖预后得到了极大改善。小和大的部分子宫中隔患者之间的生殖预后无显著差异。不孕患者和流产患者的生殖预后也相似。

结论

本研究表明,子宫中隔部分切除术和不孕患者的宫腔镜子宫成形术可显著改善生殖预后,与中隔大小无关,且生殖预后与既往产科史无关。

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