Little B B, Snell L M, Rosenfeld C R, Gilstrap L C, Gant N F
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.
Am J Dis Child. 1990 Oct;144(10):1142-6. doi: 10.1001/archpedi.1990.02150340088030.
A clinically distinct constellation of major and minor anomalies, termed the fetal alcohol syndrome, occurs among infants whose mothers abuse alcohol during pregnancy. In addition, significantly higher rates of pregnancy complications, including perinatal deaths and fetal growth retardation, occur among these women and their offspring. We studied the medical records of 40 infants born to 38 alcohol abusers and the frequency of characteristics associated with fetal alcohol syndrome. Physical examinations of 6 infants revealed primary features consistent with a diagnosis of fetal alcohol syndrome. Postnatal growth and development were very poor in 17 (50%) of 34 liveborn alcohol-exposed infants. The diagnosis of fetal alcohol syndrome did not appear in the medical records of any of these infants despite the fact that the mothers' obstetric records included a history of alcohol abuse during pregnancy. This finding emphasizes the importance of good communication between obstetric and pediatric medical staff at this hospital, particularly when providing care for pregnant women and newborn infants at high risk for complications due to maternal alcohol or other drug abuse.
一种临床上具有明显特征的主要和次要异常组合,称为胎儿酒精综合征,出现在母亲在孕期酗酒的婴儿中。此外,这些女性及其后代出现妊娠并发症(包括围产期死亡和胎儿生长受限)的几率显著更高。我们研究了38名酗酒者所生的40名婴儿的病历以及与胎儿酒精综合征相关特征的出现频率。对6名婴儿的体格检查发现了与胎儿酒精综合征诊断相符的主要特征。在34名存活的酒精暴露婴儿中,有17名(50%)出生后的生长发育非常差。尽管母亲的产科记录中有孕期酗酒史,但这些婴儿的病历中均未出现胎儿酒精综合征的诊断。这一发现强调了该医院产科和儿科医护人员之间良好沟通的重要性,尤其是在为因母亲酗酒或其他药物滥用而有并发症高风险的孕妇和新生儿提供护理时。