Programa de Pós-Graduação em Microbiologia Aplicada à Agropecuária, Universidade Estadual Paulista , Jaboticabal, SP , Brasil;
Braz J Microbiol. 2011 Jan;42(1):282-9. doi: 10.1590/S1517-83822011000100036.
Columnaris disease is one of the main causes of mortality in tilapia rearing and is responsible for large economic losses worldwide. Hematology is a tool that makes it possible to study organisms' physiological responses to pathogens. It may assist in making diagnoses and prognoses on diseases in fish populations. The hematological variables of nile tilapia were studied in specimens with a clinical diagnosis of columnaris disease and in specimens that were disease-free. The total erythrocyte count, hemoglobin rate, hematocrit percentage, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), organic defense blood cell percentages (leukocytes and thrombocytes) and hepatosomatic and splenosomatic index were determined. The results showed that there were changes in the erythrocytic series and in organic defense blood cells, in the fish infected with the bacterium, with reductions in erythrocytic variables and significant increases in the numbers of circulating lymphocytes and neutrophils.
柱状病是罗非鱼养殖中主要的致死原因之一，也是造成世界范围内经济损失的主要原因。血液学是一种研究生物体对病原体生理反应的工具。它可以帮助对鱼类种群的疾病进行诊断和预后。对患有柱状病临床诊断的罗非鱼样本和无病的罗非鱼样本进行了血液学变量研究。测定了总红细胞计数、血红蛋白率、血细胞比容百分比、平均红细胞血红蛋白（MCH）、平均红细胞血红蛋白浓度（MCHC）、平均红细胞体积（MCV）、有机防御血细胞百分比（白细胞和血小板）以及肝体和脾体指数。结果表明，受细菌感染的鱼类的红细胞系列和有机防御血细胞发生了变化，红细胞变量减少，循环淋巴细胞和中性粒细胞数量显著增加。
