A critical study on RO-4-1284 antagonism in mice.
作者信息
Colpaert F C, Lenaerts F M, Niemegeers C J, Janssen P A
出版信息
Arch Int Pharmacodyn Ther. 1975 May;215(1):40-90.
PMID:240331
Abstract
Ro-4-1284 is found to produce ptosis, hypothermia, sedation and miosis in mice, and the antagonsim to these symptoms is investigated. The study reports the differential effects of various pharmacologically distinct classes of compounds. The relevance of this type of experiments to possible antidepressant drug activity is discussed.
摘要
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