体外肺灌注增加了肺移植供体库：分析其对肺移植项目的潜在及实际影响。
Ex vivo lung perfusion increases the pool of lung grafts: analysis of its potential and real impact on a lung transplant program.
作者信息
Boffini M, Ricci D, Barbero C, Bonato R, Ribezzo M, Mancuso E, Attisani M, Simonato E, Magistroni P, Mansouri M, Solidoro P, Baldi S, Pasero D, Amoroso A, Rinaldi M
机构信息
Cardiac Surgery Department, Città della Salute e della Scienza, Turin, Italy.
出版信息
Transplant Proc. 2013 Sep;45(7):2624-6. doi: 10.1016/j.transproceed.2013.08.004.
BACKGROUND
Among the strategies to increase the number of lung transplants, ex vivo lung perfusion (EVLP) represents a novel technique to expand the donor pool.
METHODS
Data from donors referred to our center were retrospectively analyzed to identify grafts that could potentially be potentially reconditioned by EVLP and for comparison with those obtained by clinical application of EVLP program in our center.
RESULTS
Among 75 rejected lungs, 23 organs have been identified as potentially treatable with EVLP with a hypothetic increase of lung transplant activity of 53%. After the introduction of the EVLP program in our center, lung transplantation with reconditioned grafts was performed in 7 (23%) patients with a 30% increase in transplant procedures.
CONCLUSION
Although less than expected, EVLP increased the number of lungs suitable for transplantation.
背景
在增加肺移植数量的策略中，体外肺灌注（EVLP）是一种扩大供体库的新技术。
方法
对转诊至我们中心的供体数据进行回顾性分析，以确定可能通过EVLP进行修复的移植物，并与我们中心EVLP计划临床应用所获得的移植物进行比较。
结果
在75个被拒绝的肺中，23个器官被确定为可用EVLP进行潜在治疗，假设肺移植活动增加53%。在我们中心引入EVLP计划后，7名（23%）患者接受了经修复移植物的肺移植，移植手术增加了30%。
结论
尽管低于预期，但EVLP增加了适合移植的肺的数量。
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