School of Public Health and Social Work, Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology, Brisbane, Australia.
BJOG. 2013 Dec;120(13):1631-41. doi: 10.1111/1471-0528.12397. Epub 2013 Aug 20.
To quantify the short-term effects of maternal exposure to heatwave on preterm birth.
An ecological study.
A population-based study in Brisbane, Australia.
All pregnant women who had a spontaneous singleton live birth in Brisbane between November and March in 2000-2010 were studied.
Daily data on pregnancy outcomes, meteorological factors, and ambient air pollutants were obtained. The Cox proportional hazards regression model with time-dependent variables was used to examine the short-term impact of heatwave on preterm birth. A series of cut-off temperatures and durations were used to define heatwave. Multivariable analyses were also performed to adjust for socio-economic factors, demographic factors, meteorological factors, and ambient air pollutants.
Spontaneous preterm births.
The adjusted hazard ratios (HRs) ranged from 1.13 (95% CI 1.03-1.24) to 2.00 (95% CI 1.37-2.91) by using different heatwave definitions, after controlling for demographic, socio-economic, and meteorological factors, and air pollutants.
Heatwave was significantly associated with preterm birth: the associations were robust to the definitions of heatwave. The threshold temperatures, instead of duration, could be more likely to influence the evaluation of birth-related heatwaves. The findings of this study may have significant public health implications as climate change progresses.
量化母亲暴露于热浪对早产的短期影响。
生态研究。
澳大利亚布里斯班的一项基于人群的研究。
研究对象为 2000 年至 2010 年 11 月至 3 月期间在布里斯班自然单胎活产的所有孕妇。
获取妊娠结局、气象因素和环境空气污染物的每日数据。采用时变变量的 Cox 比例风险回归模型来检验热浪对早产的短期影响。使用一系列截止温度和持续时间来定义热浪。还进行了多变量分析，以调整社会经济因素、人口统计学因素、气象因素和环境空气污染物。
自发性早产。
在控制人口统计学、社会经济和气象因素以及空气污染物后，使用不同的热浪定义，调整后的危害比（HR）范围为 1.13（95%CI 1.03-1.24）至 2.00（95%CI 1.37-2.91）。
热浪与早产显著相关：这些关联在热浪的定义上是稳健的。与持续时间相比，阈值温度更有可能影响与分娩相关的热浪评估。随着气候变化的进展，本研究的结果可能具有重要的公共卫生意义。
