Graduate School of Health and Nutrition Sciences, Nakamura Gakuen University, 5-7-1 Befu, Jonan-ku, Fukuoka, 814-0198, Japan.
Lipids Health Dis. 2013 Sep 14;12:134. doi: 10.1186/1476-511X-12-134.
Nutritional guidance and diet control play important roles in the treatment of obesity and non-alcoholic fatty liver. However, in Japan, nutritional guidance is difficult to provide in practice. Therefore, we evaluated the effects of providing the 'once-a-day' intervention of a healthy lunch on various metabolic parameters.
For a 1-month preparatory period, 10 subjects generally consumed the lunches that were provided by the worksite cafeteria. This was followed by a 1-week washout period, after which, the subjects consumed healthy, low-calorie, well-balanced lunches for a 1-month test period. After the preparatory and test periods, blood samples were obtained from all subjects. The serum levels of indices relevant to metabolic syndrome and fatty liver were measured.
Serum alanine aminotransferase activity significantly decreased by 20.3% after the healthy intervention. However, the indices of metabolic syndrome did not significantly change. Analysis of the relationship between serum alanine aminotransferase activity and nutrient content indicated that the improvement of serum alanine aminotransferase status was due to the higher vegetable content and lower animal-source protein of the meals provided.
In summary, the 'once-a-day' intervention of providing a healthy lunch improved serum alanine aminotransferase status. A diet high in vegetables and low in animal-based protein is important in maintaining a healthy condition.
营养指导和饮食控制在肥胖和非酒精性脂肪肝的治疗中起着重要作用。然而，在日本，实际操作中很难提供营养指导。因此，我们评估了提供“一日一餐”健康午餐干预对各种代谢参数的影响。
在为期 1 个月的预备期内，10 名受试者通常食用由工作场所自助餐厅提供的午餐。接着是为期 1 周的洗脱期，然后在接下来的 1 个月测试期内，受试者食用健康、低热量、均衡的午餐。在预备期和测试期结束后，所有受试者都采集了血样。测量与代谢综合征和脂肪肝相关的血清指数。
健康干预后，血清丙氨酸氨基转移酶活性显著下降 20.3%。然而，代谢综合征的指数并没有显著变化。血清丙氨酸氨基转移酶活性与营养素含量之间关系的分析表明，膳食中蔬菜含量较高、动物源蛋白质含量较低是改善血清丙氨酸氨基转移酶状态的原因。
总之，提供健康午餐的“一日一餐”干预改善了血清丙氨酸氨基转移酶状况。高蔬菜、低动物蛋白的饮食对于保持健康状态很重要。
