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人类巨噬细胞对刚地弓形虫和克氏锥虫的杀菌活性差异。

Differences in microbicidal activities of human macrophages against Toxoplasma gondii and Trypanosoma cruzi.

作者信息

Israelski D M, Araujo F G, Wachtel J S, Heinrichs L, Remington J S

机构信息

Department of Obstetrics and Gynecology, Palo Alto Medical Clinic, California.

出版信息

Infect Immun. 1990 Jan;58(1):263-5. doi: 10.1128/iai.58.1.263-265.1990.

Abstract

The microbicidal activities of normal human pelvic macrophages against infection by the intracellular protozoa Toxoplasma gondii and Trypanosoma cruzi were examined. Macrophages allowed infection by T. gondii and yet possessed remarkable microbicidal activity against this organism. In contrast, human macrophages were not microbicidal against T. cruzi.

摘要

研究了正常人盆腔巨噬细胞对细胞内原生动物刚地弓形虫和克氏锥虫感染的杀菌活性。巨噬细胞允许刚地弓形虫感染,但对该生物体具有显著的杀菌活性。相比之下,人类巨噬细胞对克氏锥虫没有杀菌作用。

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