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2
Infection of murine macrophages with Toxoplasma gondii is associated with release of transforming growth factor beta and downregulation of expression of tumor necrosis factor receptors.用刚地弓形虫感染小鼠巨噬细胞与转化生长因子β的释放及肿瘤坏死因子受体表达的下调有关。
Infect Immun. 1993 Oct;61(10):4126-30. doi: 10.1128/iai.61.10.4126-4130.1993.
3
Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii.羟基萘醌566C80对刚地弓形虫速殖子和组织包囊具有显著的体外和体内活性。
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本文引用的文献

1
Connective tissue reactions in normal and immunized mice to a reticulotropic strain of Trypanosoma cruzi.正常和免疫小鼠对克氏锥虫网状嗜性菌株的结缔组织反应。
J Infect Dis. 1955 May-Jun;96(3):199-226. doi: 10.1093/infdis/96.3.199.
2
Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens.正常巨噬细胞未能触发氧化代谢爆发：细胞内病原体存活的可能机制。
J Exp Med. 1980 Feb 1;151(2):328-46. doi: 10.1084/jem.151.2.328.
3
Trypanosoma cruzi: induction of microbicidal activity in human mononuclear phagocytes.克氏锥虫：诱导人类单核吞噬细胞的杀菌活性。
J Immunol. 1982 May;128(5):2142-6.
4
Effect of normal and activated human macrophages on Toxoplasma gondii.正常及活化的人类巨噬细胞对刚地弓形虫的作用。
J Exp Med. 1974 May 1;139(5):1154-74. doi: 10.1084/jem.139.5.1154.
5
Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma.艾滋病患者组织巨噬细胞的激活：艾滋病肺泡巨噬细胞对淋巴因子和γ干扰素的体外反应。
J Immunol. 1985 Oct;135(4):2374-7.
6
Nonoxidative microbicidal activity in normal human alveolar and peritoneal macrophages.正常人肺泡巨噬细胞和腹膜巨噬细胞的非氧化杀菌活性。
Infect Immun. 1987 Jul;55(7):1635-40. doi: 10.1128/iai.55.7.1635-1640.1987.
7
Oxygen-independent killing by alveolar macrophages.肺泡巨噬细胞的非氧依赖性杀伤作用。
J Exp Med. 1986 May 1;163(5):1113-31. doi: 10.1084/jem.163.5.1113.

人类巨噬细胞对刚地弓形虫和克氏锥虫的杀菌活性差异。

Differences in microbicidal activities of human macrophages against Toxoplasma gondii and Trypanosoma cruzi.

作者信息

Israelski D M, Araujo F G, Wachtel J S, Heinrichs L, Remington J S

机构信息

Department of Obstetrics and Gynecology, Palo Alto Medical Clinic, California.

出版信息

Infect Immun. 1990 Jan;58(1):263-5. doi: 10.1128/iai.58.1.263-265.1990.

DOI:10.1128/iai.58.1.263-265.1990
PMID:2403533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC258441/
Abstract

The microbicidal activities of normal human pelvic macrophages against infection by the intracellular protozoa Toxoplasma gondii and Trypanosoma cruzi were examined. Macrophages allowed infection by T. gondii and yet possessed remarkable microbicidal activity against this organism. In contrast, human macrophages were not microbicidal against T. cruzi.

摘要

研究了正常人盆腔巨噬细胞对细胞内原生动物刚地弓形虫和克氏锥虫感染的杀菌活性。巨噬细胞允许刚地弓形虫感染，但对该生物体具有显著的杀菌活性。相比之下，人类巨噬细胞对克氏锥虫没有杀菌作用。