编码分枝杆菌抗原85复合物蛋白的三个独立基因的证据。
Evidence for three separate genes encoding the proteins of the mycobacterial antigen 85 complex.
作者信息
Wiker H G, Sletten K, Nagai S, Harboe M
机构信息
Institute of Immunology and Rheumatology, University of Oslo, Norway.
出版信息
Infect Immun. 1990 Jan;58(1):272-4. doi: 10.1128/iai.58.1.272-274.1990.
Abstract
The secreted Mycobacterium bovis BCG antigen 85 complex, which is known to bind to human fibronectin, consists of three closely related cross-reacting antigens. Amino-terminal sequence analysis of the purified proteins showed distinct differences. Data are presented to show that the three components are produced by individual cells, which indicates that three separate genes are involved.
摘要
已知可与人纤连蛋白结合的分泌型牛分枝杆菌卡介苗抗原85复合物由三种密切相关的交叉反应抗原组成。对纯化蛋白进行的氨基末端序列分析显示出明显差异。所提供的数据表明这三种成分是由单个细胞产生的，这表明涉及三个不同的基因。
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