结核分枝杆菌单克隆杂交瘤抗体的产生及部分特性分析
Production and partial characterization of monoclonal hybridoma antibodies to Mycobacterium tuberculosis.
作者信息
Schou C, Yuan Z L, Andersen A B, Bennedsen J
出版信息
Acta Pathol Microbiol Immunol Scand C. 1985 Dec;93(6):265-72. doi: 10.1111/j.1699-0463.1985.tb02955.x.
Abstract
The production and partial characterization of monoclonal hybridoma antibodies against Mycobacterium tuberculosis is described. 30 clones have been produced. Their reactivity towards M. tuberculosis antigens have been tested in immunoblotting from SDS-PAGE, in crossed immunoelectrophoresis and in ELISA. The Mab's separated into four reactivity groups, one of which may be relevant in assays for antigen specific for M. tuberculosis.
摘要
本文描述了抗结核分枝杆菌单克隆杂交瘤抗体的产生及部分特性。已产生30个克隆。通过SDS - PAGE免疫印迹、交叉免疫电泳和ELISA检测了它们对结核分枝杆菌抗原的反应性。这些单克隆抗体分为四个反应性组，其中一组可能与结核分枝杆菌特异性抗原的检测有关。
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