Max Rubner-Institut, Federal Research Institute of Nutrition and Food, Department of Safety and Quality of Fruits and Vegetables, Haid-und-Neu-str. 09, 76131, Karlsruhe, Germany.
Int J Food Microbiol. 2013 Sep 16;166(3):407-12. doi: 10.1016/j.ijfoodmicro.2013.07.019. Epub 2013 Jul 29.
Seven different commercial fungicides (Aliette, Rovral, Cantus, Ortiva, Luna Experience, Fenomenal and Mancozeb) were tested for their ability to inhibit the growth of the fungal species Penicillium nordicum, Penicillium verrucosum, Verticillium dahliae and Cladosporium sp. In case of the mycotoxigenic strains P. nordicum and P. verrucosum, the biosynthesis of the mycotoxins ochratoxin and citrinin was determined. Interestingly individual fungicides were only able to inhibit the growth of the analyzed fungi to some extent. In case of P. verrucosum the fungicide "Rovral", an iprodion belonging to the substance class of imidazoles, led to a decrease in the growth rate but to a strong induction of mycotoxin biosynthesis as has been described earlier for the strobilurins. Consequently before using a given fungicide to protect crops and enhance storage life, the applicability of this chemical compound should be tested not only for its ability to inhibit fungal growth but also for its effect on level of secondary metabolite biosynthesis.
七种不同的商业杀菌剂（Aliette、Rovral、Cantus、Ortiva、Luna Experience、Fenomenal 和 Mancozeb）被测试其抑制真菌物种扩展青霉、疣孢青霉、黄萎轮枝孢和枝孢属生长的能力。对于产毒菌株扩展青霉和疣孢青霉，测定了霉菌毒素 ochratoxin 和 citrinin 的生物合成。有趣的是，个别杀菌剂只能在一定程度上抑制分析真菌的生长。对于疣孢青霉，杀菌剂“Rovral”，一种属于咪唑类物质类别的异丙定，导致生长速度下降，但正如 earlier 对 strobilurins 所描述的那样，霉菌毒素生物合成的强烈诱导。因此，在使用某种杀菌剂来保护作物和延长储存寿命之前，不仅应测试该化合物抑制真菌生长的能力，还应测试其对次生代谢物生物合成水平的影响。
